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    GMIP GEM interacting protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720380, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GMIPprovided by VGNC
    Official Full Name
    GEM interacting proteinprovided by VGNC
    Primary source
    VGNC:VGNC:72999
    See related
    Ensembl:ENSMMUG00000003036
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GMIP in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (19236471..19250665, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (19750476..19764659, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene PBX homeobox 4 Neighboring gene PHD finger-like domain-containing protein 5A pseudogene Neighboring gene uncharacterized LOC114674180 Neighboring gene lysophosphatidic acid receptor 2 Neighboring gene ATPase 13A1 Neighboring gene zinc finger protein 101-like Neighboring gene zinc finger protein 101

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GEM-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      19236471..19250665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002801144.3 → XP_002801190.3  GEM-interacting protein isoform X4

      UniProtKB/TrEMBL
      H9Z9R3
      Conserved Domains (4) summary
      smart00109
      Location:463 → 508
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      pfam03154
      Location:734 → 906
      Atrophin-1; Atrophin-1 family
      cl02570
      Location:520 → 723
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl12013
      Location:108 → 308
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_015123400.2 → XP_014978886.2  GEM-interacting protein isoform X2

      UniProtKB/TrEMBL
      H9Z9R3
      Conserved Domains (4) summary
      smart00109
      Location:489 → 534
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      pfam03154
      Location:760 → 932
      Atrophin-1; Atrophin-1 family
      cl02570
      Location:546 → 749
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl12013
      Location:108 → 308
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_015123401.2 → XP_014978887.2  GEM-interacting protein isoform X3

      UniProtKB/TrEMBL
      A0A5F8ATS2, H9Z9R3
      Related
      ENSMMUP00000081232.1, ENSMMUT00000088216.1
      Conserved Domains (4) summary
      smart00109
      Location:466 → 511
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      pfam03154
      Location:737 → 909
      Atrophin-1; Atrophin-1 family
      cl02570
      Location:523 → 726
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl12013
      Location:108 → 308
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. XM_001115784.4 → XP_001115784.4  GEM-interacting protein isoform X1

      UniProtKB/TrEMBL
      F6VM79, H9Z9R3
      Related
      ENSMMUP00000004051.4, ENSMMUT00000004297.4
      Conserved Domains (4) summary
      smart00109
      Location:492 → 537
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      pfam03154
      Location:763 → 935
      Atrophin-1; Atrophin-1 family
      cl02570
      Location:549 → 752
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl12013
      Location:108 → 308
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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