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    ROBO2 roundabout guidance receptor 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719197, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ROBO2provided by VGNC
    Official Full Name
    roundabout guidance receptor 2provided by VGNC
    Primary source
    VGNC:VGNC:84067
    See related
    Ensembl:ENSMMUG00000012609
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ROBO2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (194219571..195993226, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (736117..2182802)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106995902 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114676104 Neighboring gene uncharacterized LOC114676103 Neighboring gene voltage-dependent anion-selective channel protein 1 pseudogene Neighboring gene uncharacterized LOC114676102 Neighboring gene uncharacterized LOC106995660 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114676106 Neighboring gene uncharacterized LOC114676105 Neighboring gene uncharacterized LOC106995642 Neighboring gene uncharacterized LOC106995651 Neighboring gene uncharacterized LOC114676107 Neighboring gene uncharacterized LOC106995898 Neighboring gene tubulin beta-8 chain-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    roundabout homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      194219571..195993226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843449.1 → XP_028699282.1  roundabout homolog 2 isoform X5

      UniProtKB/TrEMBL
      A0A1D5RF65, H9ESS7
      Related
      ENSMMUP00000058959.2, ENSMMUT00000065812.2
      Conserved Domains (5) summary
      cd05726
      Location:344 → 433
      Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
      cd07693
      Location:46 → 145
      Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
      smart00410
      Location:440 → 521
      IG_like; Immunoglobulin like
      cd00063
      Location:538 → 631
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl11960
      Location:153 → 237
      Ig; Immunoglobulin domain

    2. XM_015128837.2 → XP_014984323.1  roundabout homolog 2 isoform X4

      UniProtKB/TrEMBL
      H9ESS7
      Conserved Domains (6) summary
      cd00063
      Location:545 → 638
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:159 → 162
      Ig; Ig strand A [structural motif]
      cd05726
      Location:338 → 435
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:54 → 152
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:442 → 528
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:159 → 244
      Ig; Immunoglobulin domain

    3. XM_015128834.2 → XP_014984320.1  roundabout homolog 2 isoform X3

      UniProtKB/TrEMBL
      H9ESS7
      Conserved Domains (6) summary
      cd00063
      Location:549 → 642
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:159 → 162
      Ig; Ig strand A [structural motif]
      cd05726
      Location:342 → 439
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:54 → 152
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:446 → 532
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:159 → 244
      Ig; Immunoglobulin domain

    4. XM_028843448.1 → XP_028699281.1  roundabout homolog 2 isoform X2

      UniProtKB/TrEMBL
      H9ESS7
      Related
      ENSMMUP00000040178.3, ENSMMUT00000047158.3
      Conserved Domains (6) summary
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:150 → 154
      Ig; Ig strand B [structural motif]
      cd05726
      Location:319 → 416
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:31 → 129
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:423 → 509
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:136 → 221
      Ig; Immunoglobulin domain

    5. XM_028843447.1 → XP_028699280.1  roundabout homolog 2 isoform X1

      UniProtKB/TrEMBL
      H9ESS7
      Conserved Domains (6) summary
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:150 → 154
      Ig; Ig strand B [structural motif]
      cd05726
      Location:319 → 416
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:31 → 129
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:423 → 509
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:136 → 221
      Ig; Immunoglobulin domain

    6. XM_015128844.2 → XP_014984330.1  roundabout homolog 2 isoform X7

      UniProtKB/TrEMBL
      F7F5B4, H9ESS7
      Related
      ENSMMUP00000016559.4, ENSMMUT00000017683.4
      Conserved Domains (6) summary
      cd00063
      Location:522 → 615
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:136 → 139
      Ig; Ig strand A [structural motif]
      cd05726
      Location:315 → 412
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:31 → 129
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:419 → 505
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:136 → 221
      Ig; Immunoglobulin domain

    7. XM_015128840.2 → XP_014984326.1  roundabout homolog 2 isoform X6

      UniProtKB/TrEMBL
      H9ESS7
      Related
      ENSMMUP00000044684.2, ENSMMUT00000056581.2
      Conserved Domains (6) summary
      cd00063
      Location:526 → 619
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:136 → 139
      Ig; Ig strand A [structural motif]
      cd05726
      Location:319 → 416
      IgI_4_Robo; Fourth immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; member of the I-set of Ig superfamily (IgSF) domains
      cd07693
      Location:31 → 129
      IgC_1_Robo; First immunoglobulin (Ig)-like constant domain in Robo (roundabout) receptors, and similar domains
      cd20952
      Location:423 → 509
      IgI_5_Robo; Fifth Ig-like domain of Roundabout (Robo) homolog 1/2, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:136 → 221
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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