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    PLCH1 phospholipase C eta 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707243, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLCH1provided by VGNC
    Official Full Name
    phospholipase C eta 1provided by VGNC
    Primary source
    VGNC:VGNC:76132
    See related
    Ensembl:ENSMMUG00000018341
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLCH1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (57776533..58030171, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (142490172..142808623, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene polyadenylate-binding protein 1 pseudogene Neighboring gene uncharacterized LOC106997057 Neighboring gene ferritin heavy chain pseudogene Neighboring gene chromosome 2 C3orf33 homolog Neighboring gene solute carrier family 33 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
    Names
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1
    1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      57776533..58030171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843796.1 → XP_028699629.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X8

      UniProtKB/TrEMBL
      A0A5F7ZL81
      Related
      ENSMMUP00000065929.1, ENSMMUT00000097522.1
      Conserved Domains (4) summary
      cd00275
      Location:689 → 813
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:310 → 659
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    2. XM_015131849.2 → XP_014987335.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X2

      UniProtKB/TrEMBL
      G7MJG4
      Conserved Domains (4) summary
      cd00275
      Location:743 → 867
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    3. XM_015131848.2 → XP_014987334.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X1

      UniProtKB/TrEMBL
      G7MJG4
      Conserved Domains (4) summary
      cd00275
      Location:743 → 867
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    4. XM_015131852.2 → XP_014987338.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X7

      UniProtKB/TrEMBL
      G7MJG4
      Conserved Domains (4) summary
      cd00275
      Location:731 → 855
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:298 → 701
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:146 → 286
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:22 → 128
      PH-like; Pleckstrin homology-like domain

    5. XM_028843795.1 → XP_028699628.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X6

      UniProtKB/TrEMBL
      G7MJG4
      Conserved Domains (4) summary
      cd00275
      Location:713 → 837
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:280 → 683
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:128 → 268
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:4 → 110
      PH-like; Pleckstrin homology-like domain

    6. XM_015131851.2 → XP_014987337.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X4

      UniProtKB/TrEMBL
      F7H670, G7MJG4
      Related
      ENSMMUP00000024112.4, ENSMMUT00000025773.4
      Conserved Domains (4) summary
      cd00275
      Location:743 → 867
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    7. XM_015131854.2 → XP_014987340.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X9

      UniProtKB/TrEMBL
      A0A5F7ZFJ1
      Conserved Domains (4) summary
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      PLN02230
      Location:285 → 853
      PLN02230; phosphoinositide phospholipase C 4
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    8. XM_015131853.2 → XP_014987339.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X9

      UniProtKB/TrEMBL
      A0A5F7ZFJ1
      Conserved Domains (4) summary
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      PLN02230
      Location:285 → 853
      PLN02230; phosphoinositide phospholipase C 4
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    9. XM_028843794.1 → XP_028699627.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X5

      UniProtKB/TrEMBL
      G7MJG4
      Conserved Domains (4) summary
      cd00275
      Location:743 → 867
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:310 → 713
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:158 → 298
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:34 → 140
      PH-like; Pleckstrin homology-like domain

    10. XM_015131850.2 → XP_014987336.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZJF1, G7MJG4
      Related
      ENSMMUP00000064744.1, ENSMMUT00000098015.1
      Conserved Domains (4) summary
      cd00275
      Location:731 → 855
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:298 → 701
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:146 → 286
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:22 → 128
      PH-like; Pleckstrin homology-like domain

    11. XM_028843798.1 → XP_028699631.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X10

      UniProtKB/TrEMBL
      A0A5F7ZFJ1
      Related
      ENSMMUP00000063951.1, ENSMMUT00000099544.1
      Conserved Domains (4) summary
      cd00275
      Location:731 → 855
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:298 → 701
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:146 → 286
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:22 → 128
      PH-like; Pleckstrin homology-like domain

    12. XM_015131855.2 → XP_014987341.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X10

      UniProtKB/TrEMBL
      A0A5F7ZFJ1
      Conserved Domains (4) summary
      cd00275
      Location:731 → 855
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08632
      Location:298 → 701
      PI-PLCc_eta1; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta1
      cd16220
      Location:146 → 286
      EFh_PI-PLCeta1; EF-hand motif found in phosphoinositide phospholipase C eta 1 (PI-PLC-eta1)
      cl17171
      Location:22 → 128
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
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