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    ADA adenosine deaminase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717897, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAprovided by VGNC
    Official Full Name
    adenosine deaminaseprovided by VGNC
    Primary source
    VGNC:VGNC:84539
    See related
    Ensembl:ENSMMUG00000010603
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADA in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (79851161..79883957, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (19815324..19871143)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene serine incorporator 3 Neighboring gene uncharacterized LOC114670484 Neighboring gene cAMP-dependent protein kinase inhibitor gamma Neighboring gene uncharacterized LOC114670485 Neighboring gene U6 spliceosomal RNA Neighboring gene cellular communication network factor 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables adenosine deaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenosine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hypoxanthine salvage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of adenosine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in purine ribonucleoside monophosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenosine deaminase
    XP_028684274.1
    XP_028684275.1
    XP_028684276.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      79851161..79883957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828443.1 → XP_028684276.1  adenosine deaminase isoform X3

      Conserved Domains (1) summary
      cl00281
      Location:26 → 212
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

    2. XM_028828442.1 → XP_028684275.1  adenosine deaminase isoform X2

      UniProtKB/TrEMBL
      F7CBG9, H9EX25, H9YV62
      Related
      ENSMMUP00000013898.3, ENSMMUT00000014833.4
      Conserved Domains (1) summary
      cl00281
      Location:9 → 323
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...

    3. XM_028828441.1 → XP_028684274.1  adenosine deaminase isoform X1

      UniProtKB/TrEMBL
      A0A1D5QEF0, H9EX25, H9YV62
      Related
      ENSMMUP00000046419.2, ENSMMUT00000063229.2
      Conserved Domains (1) summary
      cl00281
      Location:9 → 347
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    Nucleotide Protein
    Heading Accession and Version

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