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    ITGB2 integrin subunit beta 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710577, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITGB2provided by VGNC
    Official Full Name
    integrin subunit beta 2provided by VGNC
    Primary source
    VGNC:VGNC:73786
    See related
    Ensembl:ENSMMUG00000000951
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITGB2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (1782781..1829450)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (1774315..1820871)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene SLX9 ribosome biogenesis factor Neighboring gene uncharacterized protein encoded by LINC01547-like Neighboring gene PTTG1 interacting protein Neighboring gene small ubiquitin like modifier 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    integrin beta-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      1782781..1829450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132732.2 → XP_014988218.2  integrin beta-2 isoform X2

      UniProtKB/TrEMBL
      F6QYR5, H9Z8N5
      Related
      ENSMMUP00000062398.1, ENSMMUT00000081424.1
      Conserved Domains (3) summary
      smart00187
      Location:32 → 447
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:622 → 699
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:726 → 766
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    2. XM_015132731.2 → XP_014988217.2  integrin beta-2 isoform X2

      UniProtKB/TrEMBL
      F6QYR5, H9Z8N5
      Related
      ENSMMUP00000066522.1, ENSMMUT00000085003.1
      Conserved Domains (3) summary
      smart00187
      Location:32 → 447
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:622 → 699
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:726 → 766
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    3. XM_028845246.1 → XP_028701079.1  integrin beta-2 isoform X2

      UniProtKB/TrEMBL
      F6QYR5, H9Z8N5
      Related
      ENSMMUP00000075608.1, ENSMMUT00000085858.1
      Conserved Domains (3) summary
      smart00187
      Location:32 → 447
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:622 → 699
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:726 → 766
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    4. XM_015132733.2 → XP_014988219.2  integrin beta-2 isoform X2

      UniProtKB/TrEMBL
      F6QYR5, H9Z8N5
      Related
      ENSMMUP00000001277.4, ENSMMUT00000001359.4
      Conserved Domains (3) summary
      smart00187
      Location:32 → 447
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:622 → 699
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:726 → 766
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    5. XM_015132730.2 → XP_014988216.2  integrin beta-2 isoform X1

      UniProtKB/TrEMBL
      F6QYS6, H9Z8N5
      Related
      ENSMMUP00000001276.4, ENSMMUT00000001358.4
      Conserved Domains (3) summary
      smart00187
      Location:89 → 504
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:679 → 756
      Integrin_B_tail; Integrin beta tail domain
      pfam08725
      Location:783 → 823
      Integrin_b_cyt; Integrin beta cytoplasmic domain
    Nucleotide Protein
    Heading Accession and Version

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