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    LARGE1 LARGE xylosyl- and glucuronyltransferase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717403, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LARGE1provided by VGNC
    Official Full Name
    LARGE xylosyl- and glucuronyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:74236
    See related
    Ensembl:ENSMMUG00000012113
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LARGE1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (17617803..18251058)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (75160778..75798001, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 251-like Neighboring gene uncharacterized LOC107000641 Neighboring gene artemin-like Neighboring gene small nucleolar RNA SNORA76 Neighboring gene uncharacterized LOC114670368 Neighboring gene uncharacterized LOC114670590 Neighboring gene synapsin III Neighboring gene TIMP metallopeptidase inhibitor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein O-linked mannosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    xylosyl- and glucuronyltransferase LARGE1; LARGE xylosyl- and glucuronyltransferase 1
    Names
    glycosyltransferase-like protein LARGE1
    NP_001247834.1
    XP_015005496.1
    XP_015005497.1
    XP_028683253.1
    XP_028683254.1
    XP_028683255.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260905.1 → NP_001247834.1  xylosyl- and glucuronyltransferase LARGE1

      See identical proteins and their annotated locations for NP_001247834.1

      Status: PROVISIONAL

      Source sequence(s)
      JU337091
      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Related
      ENSMMUP00000015881.4, ENSMMUT00000016958.4
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      17617803..18251058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150011.2 → XP_015005497.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    2. XM_015150010.2 → XP_015005496.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Related
      ENSMMUP00000077001.1, ENSMMUT00000085157.1
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    3. XM_028827420.1 → XP_028683253.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    4. XM_028827421.1 → XP_028683254.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    5. XM_028827422.1 → XP_028683255.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      UniProtKB/TrEMBL
      F6QJZ2, F7H8S1, G7N3P5
      Related
      ENSMMUP00000037058.1, ENSMMUT00000044053.3
      Conserved Domains (2) summary
      cd06431
      Location:138 → 417
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:473 → 742
      Glyco_transf_49; Glycosyl-transferase for dystroglycan
    Nucleotide Protein
    Heading Accession and Version

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