SOX5 SRY-box transcription factor 5 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SOX5provided by VGNC
Official Full Name: SRY-box transcription factor 5provided by VGNC
Primary source: VGNC:VGNC:77843
Locus tag: EGK_03461
See related: Ensembl:ENSMMUG00000020370
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	11	NC_041764.1 (24811802..25853531, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	11	NC_027903.1 (24443959..25478660, complement)

Chromosome 11 - NC_041764.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-80033 (e-PCR)
- UniSTS:101645

SHGC-108028 (e-PCR)
- UniSTS:170522

SHGC-85675 (e-PCR)
- UniSTS:103719

WI-3881 (e-PCR)
- UniSTS:7208

RH80811 (e-PCR)
- UniSTS:84015

D12S1822 (e-PCR)
- UniSTS:26439

RH45463 (e-PCR)
- UniSTS:48716

BMS1248 (e-PCR), detects polymorphism
- UniSTS:56152

G63683 (e-PCR)
- UniSTS:140645

STS-H73926 (e-PCR)
- UniSTS:82022

Sox5 (e-PCR), detects polymorphism
- UniSTS:507239

RH103584 (e-PCR)
- UniSTS:97909

Sox5 (e-PCR), detects polymorphism
- UniSTS:265085

Sox5 (e-PCR), detects polymorphism
- UniSTS:265086

G19258 (e-PCR)
- UniSTS:55686

SHGC-155690 (e-PCR)
- UniSTS:185226

STS-N27112 (e-PCR)
- UniSTS:28330

D12S292 (e-PCR)
- UniSTS:21422

RH80021 (e-PCR)
- UniSTS:92593

G62747 (e-PCR)
- UniSTS:139724

G17656 (e-PCR)
- UniSTS:30950

WI-18056 (e-PCR)
- UniSTS:20214

D12S1591 (e-PCR), detects polymorphism
- UniSTS:49401

G62383 (e-PCR)
- UniSTS:139262

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate commitment	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of chondrocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription factor SOX-5

Names: SRY (sex determining region Y)-box 5; SRY-box 5; Transcription factor SOX-5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041764.1 Reference Mmul_10 Primary Assembly

Range

24811802..25853531 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028829333.1 → XP_028685166.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151278.2 → XP_015006764.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829319.1 → XP_028685152.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829335.1 → XP_028685168.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151284.2 → XP_015006770.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829334.1 → XP_028685167.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829332.1 → XP_028685165.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151277.2 → XP_015006763.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829328.1 → XP_028685161.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829318.1 → XP_028685151.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829325.1 → XP_028685158.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829330.1 → XP_028685163.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829324.1 → XP_028685157.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829329.1 → XP_028685162.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829323.1 → XP_028685156.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829326.1 → XP_028685159.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_001100738.4 → XP_001100738.1 transcription factor SOX-5 isoform X4

See identical proteins and their annotated locations for XP_001100738.1

UniProtKB/TrEMBL

A0A1D5Q680, A0A1D5R0L9

Related

ENSMMUP00000043546.2, ENSMMUT00000058345.2

Conserved Domains (1) summary

cd01388
Location:542 → 613

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829337.1 → XP_028685170.1 transcription factor SOX-5 isoform X7

UniProtKB/TrEMBL

H9FBX2

Conserved Domains (1) summary

cd01388
Location:508 → 579

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829320.1 → XP_028685153.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829327.1 → XP_028685160.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829322.1 → XP_028685155.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829321.1 → XP_028685154.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151285.2 → XP_015006771.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_028829336.1 → XP_028685169.1 transcription factor SOX-5 isoform X3

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:543 → 614

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_001100817.3 → XP_001100817.2 transcription factor SOX-5 isoform X2

See identical proteins and their annotated locations for XP_001100817.2

UniProtKB/TrEMBL

A0A1D5R0L9, A0A5S6RBW7, A0A8J8YH01, F7A6U3, G7N6I6

Related

ENSMMUP00000040088.3, ENSMMUT00000047058.3

Conserved Domains (1) summary

cd01388
Location:555 → 626

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151276.2 → XP_015006762.1 transcription factor SOX-5 isoform X1

UniProtKB/TrEMBL

A0A1D5R0L9

Conserved Domains (1) summary

cd01388
Location:556 → 627

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151287.2 → XP_015006773.1 transcription factor SOX-5 isoform X5

UniProtKB/TrEMBL

H9FBX2

Conserved Domains (1) summary

cd01388
Location:521 → 592

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
XM_015151288.2 → XP_015006774.1 transcription factor SOX-5 isoform X6

UniProtKB/TrEMBL

H9FBX2

Conserved Domains (1) summary

cd01388
Location:520 → 591

SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...