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    USP28 ubiquitin specific peptidase 28 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696672, updated on 17-Aug-2024

    Summary

    Official Symbol
    USP28provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 28provided by VGNC
    Primary source
    VGNC:VGNC:78745
    See related
    Ensembl:ENSMMUG00000023773
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
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    Genomic context

    See USP28 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (106942936..107020014, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (106666156..106743616, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene zw10 kinetochore protein Neighboring gene cytochrome c oxidase subunit 7A-related protein, mitochondrial pseudogene Neighboring gene claudin 25 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114672175 Neighboring gene 5-hydroxytryptamine receptor 3B

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of protein stability IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 28
    XP_001085291.1
    XP_014971230.1
    XP_014971232.1
    XP_014971234.1
    XP_014971237.1
    XP_014971238.1
    XP_014971239.1
    XP_028689824.1
    XP_028689825.1
    XP_028689826.1
    XP_028689827.1
    XP_028689828.1
    XP_028689829.1
    XP_028689830.1
    XP_028689831.1
    XP_028689832.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      106942936..107020014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833996.1XP_028689829.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X12

      Conserved Domains (1) summary
      cl02553
      Location:1315
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    2. XM_028833993.1XP_028689826.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X10

      Conserved Domains (1) summary
      cl02553
      Location:1315
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    3. XM_015115753.2XP_014971239.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X8

      UniProtKB/TrEMBL
      H9F847
      Related
      ENSMMUP00000068422.1, ENSMMUT00000088257.1
      Conserved Domains (4) summary
      cd02665
      Location:163648
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161398
      UCH; Ubiquitin carboxyl-terminal hydrolase
    4. XM_001085291.4XP_001085291.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X6

      See identical proteins and their annotated locations for XP_001085291.1

      UniProtKB/TrEMBL
      H9F847
      Related
      ENSMMUP00000031315.3, ENSMMUT00000033459.4
      Conserved Domains (4) summary
      cd02665
      Location:163648
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161398
      UCH; Ubiquitin carboxyl-terminal hydrolase
    5. XM_015115746.2XP_014971232.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QEB1
      Related
      ENSMMUP00000046380.2, ENSMMUT00000074150.2
      Conserved Domains (4) summary
      cd02665
      Location:163648
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161398
      UCH; Ubiquitin carboxyl-terminal hydrolase
    6. XM_028833997.1XP_028689830.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X13

      Conserved Domains (1) summary
      cl02553
      Location:148296
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    7. XM_028833994.1XP_028689827.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X11

      Conserved Domains (1) summary
      cl02553
      Location:148296
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    8. XM_015115752.2XP_014971238.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X7

      UniProtKB/TrEMBL
      H9F847
      Conserved Domains (4) summary
      cd02665
      Location:163649
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161399
      UCH; Ubiquitin carboxyl-terminal hydrolase
    9. XM_015115751.2XP_014971237.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X5

      UniProtKB/TrEMBL
      H9F847
      Conserved Domains (4) summary
      cd02665
      Location:163649
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161399
      UCH; Ubiquitin carboxyl-terminal hydrolase
    10. XM_015115748.2XP_014971234.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X4

      UniProtKB/TrEMBL
      H9F847
      Conserved Domains (4) summary
      cd02665
      Location:163649
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161399
      UCH; Ubiquitin carboxyl-terminal hydrolase
    11. XM_015115744.2XP_014971230.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QEB1
      Conserved Domains (4) summary
      cd02665
      Location:163649
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:161399
      UCH; Ubiquitin carboxyl-terminal hydrolase
    12. XM_028833991.1XP_028689824.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X3

      UniProtKB/TrEMBL
      G7NC29
      Conserved Domains (3) summary
      COG5207
      Location:140613
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02665
      Location:141627
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:142
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
    13. XM_028833992.1XP_028689825.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X9

      UniProtKB/TrEMBL
      F7GVG4
      Conserved Domains (2) summary
      COG5207
      Location:37510
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      cd02665
      Location:38524
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    14. XM_028833998.1XP_028689831.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X14

      UniProtKB/TrEMBL
      A0A5F7ZSV7
      Related
      ENSMMUP00000067724.1, ENSMMUT00000103111.1
      Conserved Domains (1) summary
      cl02553
      Location:148296
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    15. XM_028833995.1XP_028689828.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X11

      Conserved Domains (1) summary
      cl02553
      Location:148296
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    16. XM_028833999.1XP_028689832.1  ubiquitin carboxyl-terminal hydrolase 28 isoform X15

      Conserved Domains (3) summary
      cd02665
      Location:163397
      Peptidase_C19I; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd14355
      Location:2364
      UBA_UBP28; UBA domain found in ubiquitin carboxyl-terminal hydrolase 28 (UBP28) and similar proteins
      cl02553
      Location:163267
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...