U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SHARPIN SHANK associated RH domain interactor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713534, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SHARPINprovided by VGNC
    Official Full Name
    SHANK associated RH domain interactorprovided by VGNC
    Primary source
    VGNC:VGNC:84114
    See related
    Ensembl:ENSMMUG00000007152
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SHARPIN in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (144376590..144382135, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (143336513..143341981, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene glycosylphosphatidylinositol anchor attachment 1 Neighboring gene cytochrome c1 Neighboring gene MAF1 homolog, negative regulator of RNA polymerase III Neighboring gene HGH1 homolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein linear polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of LUBAC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    sharpin

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      144376590..144382135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028853112.1 → XP_028708945.1  sharpin isoform X5

      UniProtKB/TrEMBL
      G7N0A8
      Conserved Domains (4) summary
      smart00547
      Location:311 → 333
      ZnF_RBZ; Zinc finger domain
      cd13305
      Location:17 → 125
      PH_SHARPIN; SHANK-associated RH domain interacting protein Pleckstrin homology (PH) domain
      sd00029
      Location:312 → 331
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd01799
      Location:180 → 262
      Ubl_HOIL1; ubiquitin-like (Ubl) domain found in heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1) and similar proteins

    2. XM_015146260.2 → XP_015001746.1  sharpin isoform X2

      UniProtKB/TrEMBL
      G7N0A8
      Conserved Domains (4) summary
      smart00547
      Location:345 → 367
      ZnF_RBZ; Zinc finger domain
      sd00029
      Location:346 → 365
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam16764
      Location:13 → 125
      Sharpin_PH; Sharpin PH domain
      cl00155
      Location:234 → 294
      UBQ; Ubiquitin-like proteins

    3. XM_015146263.2 → XP_015001749.1  sharpin isoform X3

      UniProtKB/TrEMBL
      G7N0A8
      Conserved Domains (4) summary
      smart00547
      Location:344 → 366
      ZnF_RBZ; Zinc finger domain
      sd00029
      Location:345 → 364
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam16764
      Location:13 → 125
      Sharpin_PH; Sharpin PH domain
      cl00155
      Location:235 → 295
      UBQ; Ubiquitin-like proteins

    4. XM_015146261.2 → XP_015001747.1  sharpin isoform X3

      UniProtKB/TrEMBL
      G7N0A8
      Conserved Domains (4) summary
      smart00547
      Location:344 → 366
      ZnF_RBZ; Zinc finger domain
      sd00029
      Location:345 → 364
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam16764
      Location:13 → 125
      Sharpin_PH; Sharpin PH domain
      cl00155
      Location:235 → 295
      UBQ; Ubiquitin-like proteins

    5. XM_028853111.1 → XP_028708944.1  sharpin isoform X4

      UniProtKB/TrEMBL
      G7N0A8
      Conserved Domains (2) summary
      cd13305
      Location:17 → 125
      PH_SHARPIN; SHANK-associated RH domain interacting protein Pleckstrin homology (PH) domain
      cd01799
      Location:213 → 297
      Ubl_HOIL1; ubiquitin-like (Ubl) domain found in heme-oxidized IRP2 ubiquitin ligase 1 (HOIL-1) and similar proteins

    6. XM_015146259.2 → XP_015001745.1  sharpin isoform X1

      UniProtKB/TrEMBL
      F6X2J2, F7DI39, G7N0A8
      Related
      ENSMMUP00000009373.4, ENSMMUT00000009987.4
      Conserved Domains (4) summary
      smart00547
      Location:346 → 368
      ZnF_RBZ; Zinc finger domain
      sd00029
      Location:347 → 366
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam16764
      Location:13 → 125
      Sharpin_PH; Sharpin PH domain
      cl00155
      Location:235 → 295
      UBQ; Ubiquitin-like proteins

    7. XM_015146258.2 → XP_015001744.1  sharpin isoform X1

      UniProtKB/TrEMBL
      F6X2J2, F7DI39, G7N0A8
      Conserved Domains (4) summary
      smart00547
      Location:346 → 368
      ZnF_RBZ; Zinc finger domain
      sd00029
      Location:347 → 366
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam16764
      Location:13 → 125
      Sharpin_PH; Sharpin PH domain
      cl00155
      Location:235 → 295
      UBQ; Ubiquitin-like proteins

    RNA

    1. XR_003732589.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.