CELF1 CUGBP Elav-like family member 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CELF1provided by VGNC
Official Full Name: CUGBP Elav-like family member 1provided by VGNC
Primary source: VGNC:VGNC:71098
Locus tag: EGK_06290
See related: Ensembl:ENSMMUG00000011657
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: CUGBP1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (18201348..18293379)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (18456049..18548553)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results suggest that CUGBP1 is a previously unrecognized downstream effector of IFNbeta signaling in primary macrophages that likely plays a pivotal role in innate immune responses that control acute HIV/SIV replication in the brain.
Title: CUGBP1 is required for IFNbeta-mediated induction of dominant-negative CEBPbeta and suppression of SIV replication in macrophages.

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General gene information

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Markers

RH25600 (e-PCR)
- UniSTS:84245

RH69518 (e-PCR)
- UniSTS:8982

CUGBP1_2383 (e-PCR)
- UniSTS:280629

RH46584 (e-PCR)
- UniSTS:85066

RH66384 (e-PCR)
- UniSTS:50514

STS-N31747 (e-PCR)
- UniSTS:38745

Cugbp1 (e-PCR), detects polymorphism
- UniSTS:479088

X61451 (e-PCR)
- UniSTS:125827

STS-H11078 (e-PCR)
- UniSTS:1965

MARC_7541-7542:996687927:1 (e-PCR)
- UniSTS:269790

MARC_11599-11600:1002739035:1 (e-PCR)
- UniSTS:267239

SHGC-56849 (e-PCR)
- UniSTS:45311

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mRNA splice site recognition	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CUGBP Elav-like family member 1

Names: CUG triplet repeat, RNA binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

18201348..18293379

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028833429.1 → XP_028689262.1 CUGBP Elav-like family member 1 isoform X5

UniProtKB/TrEMBL

A0A5F8AJI1, F6SSD3

Related

ENSMMUP00000077559.1, ENSMMUT00000082365.1

Conserved Domains (3) summary

cd12638
Location:422 → 513

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:42 → 125

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:134 → 214

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114293.2 → XP_014969779.1 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_028833432.1 → XP_028689265.1 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114295.2 → XP_014969781.1 CUGBP Elav-like family member 1 isoform X4

UniProtKB/TrEMBL

A0A5F8AJI1, H9EM84

Conserved Domains (3) summary

cd12638
Location:390 → 481

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_028833433.1 → XP_028689266.1 CUGBP Elav-like family member 1 isoform X2

UniProtKB/TrEMBL

A0A5F8AJI1, F7HGX2, I2CTF0

Related

ENSMMUP00000015301.4, ENSMMUT00000016331.4

Conserved Domains (3) summary

cd12638
Location:394 → 485

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114294.2 → XP_014969780.1 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114290.2 → XP_014969776.1 CUGBP Elav-like family member 1 isoform X5

UniProtKB/TrEMBL

A0A5F8AJI1, F6SSD3

Related

ENSMMUP00000015304.4, ENSMMUT00000016334.4

Conserved Domains (3) summary

cd12638
Location:422 → 513

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:42 → 125

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:134 → 214

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114286.2 → XP_014969772.2 CUGBP Elav-like family member 1 isoform X3

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:391 → 482

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114287.2 → XP_014969773.2 CUGBP Elav-like family member 1 isoform X3

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:391 → 482

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114288.2 → XP_014969774.2 CUGBP Elav-like family member 1 isoform X4

UniProtKB/TrEMBL

A0A5F8AJI1, H9EM84

Conserved Domains (3) summary

cd12638
Location:390 → 481

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114289.2 → XP_014969775.2 CUGBP Elav-like family member 1 isoform X4

UniProtKB/TrEMBL

A0A5F8AJI1, H9EM84

Conserved Domains (3) summary

cd12638
Location:390 → 481

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114280.2 → XP_014969766.2 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114281.2 → XP_014969767.2 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114282.2 → XP_014969768.2 CUGBP Elav-like family member 1 isoform X1

UniProtKB/TrEMBL

A0A5F8AJI1

Conserved Domains (3) summary

cd12638
Location:395 → 486

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114283.2 → XP_014969769.2 CUGBP Elav-like family member 1 isoform X2

UniProtKB/TrEMBL

A0A5F8AJI1, F7HGX2, I2CTF0

Conserved Domains (3) summary

cd12638
Location:394 → 485

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114284.2 → XP_014969770.2 CUGBP Elav-like family member 1 isoform X2

UniProtKB/TrEMBL

A0A5F8AJI1, F7HGX2, I2CTF0

Conserved Domains (3) summary

cd12638
Location:394 → 485

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_015114285.2 → XP_014969771.2 CUGBP Elav-like family member 1 isoform X2

UniProtKB/TrEMBL

A0A5F8AJI1, F7HGX2, I2CTF0

Related

ENSMMUP00000062582.1, ENSMMUT00000096993.1

Conserved Domains (3) summary

cd12638
Location:394 → 485

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:15 → 98

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:107 → 187

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_028833430.1 → XP_028689263.1 CUGBP Elav-like family member 1 isoform X5

UniProtKB/TrEMBL

A0A5F8AJI1, F6SSD3

Conserved Domains (3) summary

cd12638
Location:422 → 513

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:42 → 125

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:134 → 214

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
XM_028833431.1 → XP_028689264.1 CUGBP Elav-like family member 1 isoform X6

UniProtKB/TrEMBL

A0A5F8AJI1, F7HGX1, I0FNK7

Related

ENSMMUP00000080909.1, ENSMMUT00000106191.1

Conserved Domains (3) summary

cd12638
Location:421 → 512

RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

cd12631
Location:42 → 125

RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins

cd12634
Location:134 → 214

RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins