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    SYNJ2 synaptojanin 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705639, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SYNJ2provided by VGNC
    Official Full Name
    synaptojanin 2provided by VGNC
    Primary source
    VGNC:VGNC:83473
    See related
    Ensembl:ENSMMUG00000007153
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SYNJ2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (64318057..64432513)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (107861759..107981634, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene sorting nexin 9 Neighboring gene uncharacterized LOC114677530 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC106998068 Neighboring gene serine active site containing 1 Neighboring gene general transcription factor IIH subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    synaptojanin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      64318057..64432513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137056.2 → XP_014992542.1  synaptojanin-2 isoform X1

      UniProtKB/TrEMBL
      F7DI71, H9EWN6
      Related
      ENSMMUP00000009370.4, ENSMMUT00000009984.4
      Conserved Domains (3) summary
      pfam02383
      Location:61 → 342
      Syja_N; SacI homology domain
      pfam08952
      Location:872 → 1008
      DUF1866; Domain of unknown function (DUF1866)
      cl00490
      Location:530 → 861
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    2. XM_015137057.2 → XP_014992543.1  synaptojanin-2 isoform X2

      UniProtKB/TrEMBL
      H9EWN6
      Related
      ENSMMUP00000058306.2, ENSMMUT00000054724.2
      Conserved Domains (3) summary
      pfam02383
      Location:61 → 342
      Syja_N; SacI homology domain
      pfam08952
      Location:872 → 1008
      DUF1866; Domain of unknown function (DUF1866)
      cl00490
      Location:530 → 861
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    3. XM_015137059.2 → XP_014992545.1  synaptojanin-2 isoform X4

      UniProtKB/TrEMBL
      H9EWN6
      Conserved Domains (3) summary
      COG5329
      Location:30 → 485
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam08952
      Location:872 → 1008
      DUF1866; Domain of unknown function (DUF1866)
      cl00490
      Location:530 → 861
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    4. XM_015137058.2 → XP_014992544.1  synaptojanin-2 isoform X4

      UniProtKB/TrEMBL
      H9EWN6
      Conserved Domains (3) summary
      COG5329
      Location:30 → 485
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam08952
      Location:872 → 1008
      DUF1866; Domain of unknown function (DUF1866)
      cl00490
      Location:530 → 861
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    5. XM_028847292.1 → XP_028703125.1  synaptojanin-2 isoform X3

      UniProtKB/TrEMBL
      G7MQ20
      Conserved Domains (5) summary
      PHA03378
      Location:1094 → 1322
      PHA03378; EBNA-3B; Provisional
      COG5329
      Location:22 → 431
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam08952
      Location:818 → 954
      DUF1866; Domain of unknown function (DUF1866)
      pfam03154
      Location:1239 → 1420
      Atrophin-1; Atrophin-1 family
      cl00490
      Location:476 → 807
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    6. XM_015137060.2 → XP_014992546.1  synaptojanin-2 isoform X5

      UniProtKB/TrEMBL
      G7MQ20
      Conserved Domains (3) summary
      pfam02383
      Location:71 → 127
      Syja_N; SacI homology domain
      pfam08952
      Location:657 → 793
      DUF1866; Domain of unknown function (DUF1866)
      cl00490
      Location:315 → 646
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    RNA

    1. XR_001444399.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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