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    PROZ protein Z, vitamin K dependent plasma glycoprotein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696982, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PROZprovided by VGNC
    Official Full Name
    protein Z, vitamin K dependent plasma glycoproteinprovided by VGNC
    Primary source
    VGNC:VGNC:76428
    See related
    Ensembl:ENSMMUG00000001039
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PROZ in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (94395207..94410759)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (94630061..94644881)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114673492 Neighboring gene coagulation factor VII Neighboring gene coagulation factor X Neighboring gene uncharacterized LOC106994402 Neighboring gene PCI domain containing 2 Neighboring gene cullin 4A Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vitamin K-dependent protein Z

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      94395207..94410759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001087442.4 → XP_001087442.2  vitamin K-dependent protein Z isoform X1

      UniProtKB/TrEMBL
      F6SB17
      Related
      ENSMMUP00000001393.4, ENSMMUT00000001482.4
      Conserved Domains (4) summary
      smart00069
      Location:22 → 86
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:95 → 123
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00089
      Location:189 → 341
      Trypsin
      pfam14670
      Location:136 → 165
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    2. XM_028837371.1 → XP_028693204.1  vitamin K-dependent protein Z isoform X2

      UniProtKB/TrEMBL
      F6SB17
      Conserved Domains (4) summary
      smart00069
      Location:22 → 86
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:95 → 123
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00089
      Location:170 → 322
      Trypsin
      pfam12662
      Location:128 → 150
      cEGF; Complement Clr-like EGF-like
    Nucleotide Protein
    Heading Accession and Version

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