U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SLIT1 slit guidance ligand 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705901, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SLIT1provided by VGNC
    Official Full Name
    slit guidance ligand 1provided by VGNC
    Primary source
    VGNC:VGNC:77643
    See related
    Ensembl:ENSMMUG00000010428
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SLIT1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (97440298..97625043, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (92489029..92673685, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-607 Neighboring gene ligand dependent nuclear receptor corepressor Neighboring gene Rho GTPase activating protein 19 Neighboring gene FRAT regulator of WNT signaling pathway 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Prefrontal-enriched SLIT1 expression in Old World monkey cortex established during the postnatal development. Sasaki T, et al. Cereb Cortex, 2010 Oct. PMID 20123755, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Roundabout binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    slit homolog 1 protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      97440298..97625043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147856.2 → XP_015003342.1  slit homolog 1 protein isoform X1

      UniProtKB/TrEMBL
      F7CX22, G7N2N7, H9ZCL4
      Related
      ENSMMUP00000013672.4, ENSMMUT00000014594.4
      Conserved Domains (9) summary
      smart00013
      Location:33 → 64
      LRRNT; Leucine rich repeat N-terminal domain
      smart00082
      Location:866 → 915
      LRRCT; Leucine rich repeat C-terminal domain
      smart00282
      Location:1189 → 1322
      LamG; Laminin G domain
      cd00054
      Location:1085 → 1119
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00116
      Location:87 → 220
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:43 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:334 → 373
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:590 → 649
      LRR_8; Leucine rich repeat
      cl15307
      Location:439 → 469
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    2. XM_028826723.1 → XP_028682556.1  slit homolog 1 protein isoform X2

      Conserved Domains (6) summary
      TIGR00864
      Location:644 → 730
      PCC; polycystin cation channel protein
      smart00013
      Location:33 → 64
      LRRNT; Leucine rich repeat N-terminal domain
      COG4886
      Location:62 → 219
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00054
      Location:1085 → 1119
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00033
      Location:43 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:590 → 649
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.