U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717037, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ABL2provided by VGNC
    Official Full Name
    ABL proto-oncogene 2, non-receptor tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:69586
    See related
    Ensembl:ENSMMUG00000006262
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ABL2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (36301590..36429395, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (188260479..188387985)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S26-like Neighboring gene FAM20B glycosaminoglycan xylosylkinase Neighboring gene uncharacterized LOC114679386 Neighboring gene torsin family 3 member A Neighboring gene protein SET pseudogene Neighboring gene UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1-like Neighboring gene uncharacterized LOC114679395 Neighboring gene 60S ribosomal protein L39 pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tyrosine-protein kinase ABL2
    Names
    v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      36301590..36429395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122847.2 → XP_014978333.1  tyrosine-protein kinase ABL2 isoform X7

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:939 → 1058
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:148 → 241
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:90 → 143
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:260 → 522
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:267 → 518
      Pkinase_Tyr; Protein tyrosine kinase

    2. XM_015122831.2 → XP_014978317.1  tyrosine-protein kinase ABL2 isoform X5

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:960 → 1079
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:169 → 262
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:111 → 164
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:281 → 543
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:288 → 539
      Pkinase_Tyr; Protein tyrosine kinase

    3. XM_015122790.2 → XP_014978276.1  tyrosine-protein kinase ABL2 isoform X1

      UniProtKB/TrEMBL
      F7AU70, G7MF68
      Related
      ENSMMUP00000037795.2, ENSMMUT00000044774.3
      Conserved Domains (5) summary
      smart00808
      Location:1063 → 1182
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:169 → 262
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:111 → 164
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:281 → 543
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:288 → 539
      Pkinase_Tyr; Protein tyrosine kinase

    4. XM_015122856.2 → XP_014978342.1  tyrosine-protein kinase ABL2 isoform X8

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:924 → 1043
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:133 → 226
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:75 → 128
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:245 → 507
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:252 → 503
      Pkinase_Tyr; Protein tyrosine kinase

    5. XM_015122815.2 → XP_014978301.1  tyrosine-protein kinase ABL2 isoform X4

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:1027 → 1146
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:133 → 226
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:75 → 128
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:245 → 507
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:252 → 503
      Pkinase_Tyr; Protein tyrosine kinase

    6. XM_015122840.2 → XP_014978326.1  tyrosine-protein kinase ABL2 isoform X6

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:945 → 1064
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:154 → 247
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:96 → 149
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:266 → 528
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:273 → 524
      Pkinase_Tyr; Protein tyrosine kinase

    7. XM_015122797.2 → XP_014978283.1  tyrosine-protein kinase ABL2 isoform X2

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:1048 → 1167
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:154 → 247
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:96 → 149
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:266 → 528
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:273 → 524
      Pkinase_Tyr; Protein tyrosine kinase

    8. XM_015122805.2 → XP_014978291.1  tyrosine-protein kinase ABL2 isoform X3

      UniProtKB/TrEMBL
      G7MF68
      Conserved Domains (5) summary
      smart00808
      Location:1042 → 1161
      FABD; F-actin binding domain (FABD)
      cd09935
      Location:148 → 241
      SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
      cd11850
      Location:90 → 143
      SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
      cd05052
      Location:260 → 522
      PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
      pfam07714
      Location:267 → 518
      Pkinase_Tyr; Protein tyrosine kinase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials