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    DEGS2 delta 4-desaturase, sphingolipid 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717222, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DEGS2provided by VGNC
    Official Full Name
    delta 4-desaturase, sphingolipid 2provided by VGNC
    Primary source
    VGNC:VGNC:108293
    See related
    Ensembl:ENSMMUG00000062581
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DEGS2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (162361632..162374512, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (162466757..162482343, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene Enah/Vasp-like Neighboring gene uncharacterized LOC114679645 Neighboring gene microRNA mir-342 Neighboring gene YY1 transcription factor Neighboring gene solute carrier family 25 member 29

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingolipid delta-4 desaturase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sphingosine hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphinganine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      162361632..162374512 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144479.2 → XP_014999965.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

      UniProtKB/TrEMBL
      A0A5F7ZY35, G7MW53
      Related
      ENSMMUP00000068233.1, ENSMMUT00000081609.1
      Conserved Domains (2) summary
      cd03508
      Location:26 → 314
      Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
      pfam08557
      Location:6 → 42
      Lipid_DES; Sphingolipid Delta4-desaturase (DES)
    Nucleotide Protein
    Heading Accession and Version

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