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    ITPR1 inositol 1,4,5-trisphosphate receptor type 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703669, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITPR1provided by VGNC
    Official Full Name
    inositol 1,4,5-trisphosphate receptor type 1provided by VGNC
    Primary source
    VGNC:VGNC:73804
    See related
    Ensembl:ENSMMUG00000012574
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITPR1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    62
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (135800578..136155662)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (61653558..62047000, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene SET domain and mariner transposase fusion gene Neighboring gene sulfatase modifying factor 1 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC114676386 Neighboring gene uncharacterized LOC114676384 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC114676385

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol 1,4,5 trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol 1,4,5-trisphosphate receptor type 1
    Names
    inositol 1,4,5-triphosphate receptor, type 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      135800578..136155662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130355.2 → XP_014985841.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X1

      UniProtKB/TrEMBL
      F7HG18
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2351 → 2610
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1974 → 2079
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    2. XM_015130362.2 → XP_014985848.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X7

      UniProtKB/TrEMBL
      F7HG18, H9FU38
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2341 → 2600
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1964 → 2069
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    3. XM_015130365.2 → XP_014985851.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X10

      UniProtKB/TrEMBL
      F6PIT4, H9YVN2
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2302 → 2561
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1925 → 2030
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    4. XM_015130363.2 → XP_014985849.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X8

      UniProtKB/TrEMBL
      F7FEK8, F7HG18, I2CT87
      Related
      ENSMMUP00000016509.4, ENSMMUT00000017629.4
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2335 → 2594
      Ion_trans; Ion transport protein
      pfam01365
      Location:461 → 650
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 418
      MIR; MIR domain
      pfam08454
      Location:1958 → 2063
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    5. XM_015130364.2 → XP_014985850.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X9

      UniProtKB/TrEMBL
      F7HG18
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2326 → 2585
      Ion_trans; Ion transport protein
      pfam01365
      Location:461 → 650
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 418
      MIR; MIR domain
      pfam08454
      Location:1949 → 2054
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    6. XM_015130366.2 → XP_014985852.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X11

      UniProtKB/TrEMBL
      F6PIT4
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2287 → 2546
      Ion_trans; Ion transport protein
      pfam01365
      Location:461 → 650
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 418
      MIR; MIR domain
      pfam08454
      Location:1910 → 2015
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    7. XM_015130356.2 → XP_014985842.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X2

      UniProtKB/TrEMBL
      F7HG18, H9FU40
      Related
      ENSMMUP00000047727.2, ENSMMUT00000061784.2
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2350 → 2609
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1973 → 2078
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    8. XM_015130361.2 → XP_014985847.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X6

      UniProtKB/TrEMBL
      F6PIT4, F7FEF3, H9FU37
      Related
      ENSMMUP00000016511.4, ENSMMUT00000017631.4
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2311 → 2570
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1934 → 2039
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    9. XM_015130357.2 → XP_014985843.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X3

      UniProtKB/TrEMBL
      F7HG18
      Related
      ENSMMUP00000039666.3, ENSMMUT00000046629.3
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2342 → 2601
      Ion_trans; Ion transport protein
      pfam01365
      Location:476 → 665
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 433
      MIR; MIR domain
      pfam08454
      Location:1965 → 2070
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    10. XM_015130359.2 → XP_014985845.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X4

      UniProtKB/TrEMBL
      F7HG18
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2336 → 2595
      Ion_trans; Ion transport protein
      pfam01365
      Location:461 → 650
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 418
      MIR; MIR domain
      pfam08454
      Location:1959 → 2064
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    11. XM_015130360.2 → XP_014985846.1  inositol 1,4,5-trisphosphate receptor type 1 isoform X5

      UniProtKB/TrEMBL
      F7HG18
      Conserved Domains (6) summary
      smart00472
      Location:231 → 287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:2327 → 2586
      Ion_trans; Ion transport protein
      pfam01365
      Location:461 → 650
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232 → 418
      MIR; MIR domain
      pfam08454
      Location:1950 → 2055
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4 → 225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    Nucleotide Protein
    Heading Accession and Version

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