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    HIPK2 homeodomain interacting protein kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716152, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HIPK2provided by VGNC
    Official Full Name
    homeodomain interacting protein kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:73391
    See related
    Ensembl:ENSMMUG00000002481
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HIPK2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (165976521..166196920, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (165914352..166103505, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene hsc70-interacting protein pseudogene Neighboring gene enhancer of rudimentary homolog pseudogene Neighboring gene C-type lectin domain family 2 member L Neighboring gene uncharacterized LOC106997690 Neighboring gene uncharacterized LOC106997689 Neighboring gene uncharacterized LOC114677045 Neighboring gene uncharacterized LOC106997691 Neighboring gene thromboxane A synthase 1 Neighboring gene poly(ADP-ribose) polymerase family member 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeodomain-interacting protein kinase 2
    XP_028702200.1
    XP_028702201.1
    XP_028702202.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      165976521..166196920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846367.1 → XP_028702200.1  homeodomain-interacting protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      H9Z813
      Related
      ENSMMUP00000003338.3, ENSMMUT00000003530.3
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    2. XM_028846369.1 → XP_028702202.1  homeodomain-interacting protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      H9Z812
      Related
      ENSMMUP00000061338.1, ENSMMUT00000102703.1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    3. XM_028846368.1 → XP_028702201.1  homeodomain-interacting protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      F7HGU8
      Conserved Domains (1) summary
      cd14227
      Location:176 → 530
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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