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    TFEC transcription factor EC [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704124, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFECprovided by VGNC
    Official Full Name
    transcription factor ECprovided by VGNC
    Primary source
    VGNC:VGNC:81769
    See related
    Ensembl:ENSMMUG00000038489
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TFEC in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (142186907..142341190, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (141514422..141713989, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997608 Neighboring gene uncharacterized LOC106997609 Neighboring gene uncharacterized LOC114677015 Neighboring gene uncharacterized LOC106997619 Neighboring gene testin LIM domain protein Neighboring gene uncharacterized LOC106997618

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor EC

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      142186907..142341190 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846203.1 → XP_028702036.1  transcription factor EC isoform X2

      UniProtKB/TrEMBL
      A0A1D5QQI9, A0A5F8AKB0
      Related
      ENSMMUP00000050317.2, ENSMMUT00000054386.2
      Conserved Domains (3) summary
      cd00083
      Location:198 → 258
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:332 → 393
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:6 → 87
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    2. XM_028846202.1 → XP_028702035.1  transcription factor EC isoform X1

      UniProtKB/TrEMBL
      A0A1D5QUV2, A0A5F8AKB0
      Related
      ENSMMUP00000051832.2, ENSMMUT00000069831.2
      Conserved Domains (3) summary
      cd00083
      Location:227 → 287
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:361 → 422
      DUF3371; Domain of unknown function (DUF3371)
      pfam15951
      Location:6 → 155
      MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

    3. XM_001101140.4 → XP_001101140.2  transcription factor EC isoform X3

      UniProtKB/TrEMBL
      G7MM57
      Conserved Domains (2) summary
      cd00083
      Location:137 → 197
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:225 → 344
      DUF3371; Domain of unknown function (DUF3371)

    4. XM_015134775.2 → XP_014990261.1  transcription factor EC isoform X4

      UniProtKB/TrEMBL
      G7MM57
      Conserved Domains (3) summary
      cd00083
      Location:108 → 168
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam11851
      Location:196 → 315
      DUF3371; Domain of unknown function (DUF3371)
      cl21462
      Location:164 → 195
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    5. XM_015134776.2 → XP_014990262.1  transcription factor EC isoform X5

      UniProtKB/TrEMBL
      G7MM57
      Conserved Domains (2) summary
      pfam11851
      Location:158 → 277
      DUF3371; Domain of unknown function (DUF3371)
      cd18925
      Location:69 → 153
      bHLHzip_TFEC; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EC (TFEC) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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