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    PDLIM2 PDZ and LIM domain 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708652, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDLIM2provided by VGNC
    Official Full Name
    PDZ and LIM domain 2provided by VGNC
    Primary source
    VGNC:VGNC:82203
    See related
    Ensembl:ENSMMUG00000018520
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PDLIM2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (22763619..22779254)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (22497034..22512679)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3 catalytic subunit gamma Neighboring gene transcription factor BTF3 pseudogene Neighboring gene sorbin and SH3 domain containing 3 Neighboring gene chromosome 8 C8orf58 homolog Neighboring gene cell cycle and apoptosis regulator 2 Neighboring gene bridging integrator 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables muscle alpha-actinin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in muscle structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of filamentous actin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PDZ and LIM domain protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      22763619..22779254
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144958.2 → XP_015000444.2  PDZ and LIM domain protein 2 isoform X1

      UniProtKB/TrEMBL
      F7A2X3
      Related
      ENSMMUP00000024368.4, ENSMMUT00000026041.4
      Conserved Domains (4) summary
      cd09449
      Location:536 → 588
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      PHA03378
      Location:109 → 242
      PHA03378; EBNA-3B; Provisional
      cd00992
      Location:259 → 330
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:435 → 505
      DUF4749; Domain of unknown function (DUF4749)

    2. XM_015144959.2 → XP_015000445.2  PDZ and LIM domain protein 2 isoform X2

      Conserved Domains (3) summary
      PHA03378
      Location:109 → 242
      PHA03378; EBNA-3B; Provisional
      cd00992
      Location:259 → 330
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:435 → 507
      DUF4749; Domain of unknown function (DUF4749)

    3. XM_015144962.2 → XP_015000448.2  PDZ and LIM domain protein 2 isoform X3

      Conserved Domains (3) summary
      cd09449
      Location:435 → 487
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      cd00992
      Location:158 → 229
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:334 → 404
      DUF4749; Domain of unknown function (DUF4749)

    4. XM_015144963.2 → XP_015000449.2  PDZ and LIM domain protein 2 isoform X4

      Conserved Domains (3) summary
      cd09449
      Location:430 → 482
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      cd00992
      Location:153 → 224
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:329 → 399
      DUF4749; Domain of unknown function (DUF4749)

    5. XM_015144964.2 → XP_015000450.1  PDZ and LIM domain protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A5K1V083, F7A2Y2, G7N0N8, H9EV60
      Related
      ENSMMUP00000024367.4, ENSMMUT00000026040.4
      Conserved Domains (3) summary
      cd09449
      Location:286 → 338
      LIM_Mystique; The LIM domain of Mystique, a subfamily of ALP LIM domain proteins
      cd00992
      Location:9 → 80
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:202 → 255
      DUF4749; Domain of unknown function (DUF4749)
    Nucleotide Protein
    Heading Accession and Version

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