ANXA1 annexin A1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ANXA1provided by VGNC
Official Full Name: annexin A1provided by VGNC
Primary source: VGNC:VGNC:69944
See related: Ensembl:ENSMMUG00000012667
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	15	NC_041768.1 (88561712..88580580)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	15	NC_027907.1 (89353791..89373208)

Chromosome 15 - NC_041768.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings suggest that ANXA1 signaling is dysfunctional in simian immunodeficiency virus infection, and may contribute to chronic inflammation in periphery and with immune dysfunction in the gut mucosa.
Title: Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection.

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General gene information

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Markers

SHGC-13051 (e-PCR)
- UniSTS:1028

STS-U25414 (e-PCR)
- UniSTS:64820

ANXA1 (e-PCR)
- UniSTS:509949

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cadherin binding involved in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium-dependent phospholipid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phospholipase A2 inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA duplex unwinding	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in alpha-beta T cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in arachidonate secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to glucocorticoid stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to hydrogen peroxide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to vascular endothelial growth factor stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endocrine pancreas development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gliogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in granulocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hepatocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in insulin secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in keratinocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in myoblast migration involved in skeletal muscle regeneration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of T-helper 2 cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of exocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of phospholipase A2 activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil clearance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of G1/S transition of mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T-helper 1 cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell migration involved in sprouting angiogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of interleukin-2 production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of neutrophil apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of prostaglandin biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of vesicle fusion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of wound healing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in prolactin secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in prostate gland development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of hormone secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of interleukin-1 production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of leukocyte migration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to X-ray	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to estradiol	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to interleukin-1	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to peptide hormone	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed