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    EIF5B eukaryotic translation initiation factor 5B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714129, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EIF5Bprovided by VGNC
    Official Full Name
    eukaryotic translation initiation factor 5Bprovided by VGNC
    Primary source
    VGNC:VGNC:72148
    See related
    Ensembl:ENSMMUG00000018946
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EIF5B in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (3157503..3220969)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (94605124..94668776)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene lysozyme g1 Neighboring gene thioredoxin domain containing 9 Neighboring gene REV1 DNA directed polymerase Neighboring gene 60S ribosomal protein L36a-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 5B
    NP_001248539.1
    XP_014968397.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261610.1 → NP_001248539.1  eukaryotic translation initiation factor 5B

      See identical proteins and their annotated locations for NP_001248539.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048809
      UniProtKB/TrEMBL
      A0A1D5Q0Z8, A0A5F7ZUP7
      Related
      ENSMMUP00000068883.1, ENSMMUT00000080381.1
      Conserved Domains (6) summary
      cd01887
      Location:633 → 846
      IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
      PRK04004
      Location:628 → 1203
      PRK04004; translation initiation factor IF-2; Validated
      pfam08070
      Location:110 → 171
      DTHCT; DTHCT (NUC029) region
      pfam11987
      Location:967 → 1068
      IF-2; Translation-initiation factor 2
      cd03703
      Location:856 → 966
      aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5
      cd16266
      Location:1093 → 1187
      IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      3157503..3220969
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015112911.2 → XP_014968397.1  eukaryotic translation initiation factor 5B isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q0Z8
      Conserved Domains (6) summary
      cd01887
      Location:632 → 845
      IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
      PRK04004
      Location:627 → 1202
      PRK04004; translation initiation factor IF-2; Validated
      pfam08070
      Location:110 → 171
      DTHCT; DTHCT (NUC029) region
      pfam11987
      Location:966 → 1067
      IF-2; Translation-initiation factor 2
      cd03703
      Location:855 → 965
      aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5
      cd16266
      Location:1092 → 1186
      IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5
    Nucleotide Protein
    Heading Accession and Version

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