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    FGD6 FYVE, RhoGEF and PH domain containing 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712132, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FGD6provided by VGNC
    Official Full Name
    FYVE, RhoGEF and PH domain containing 6provided by VGNC
    Primary source
    VGNC:VGNC:72548
    See related
    Ensembl:ENSMMUG00000018901
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FGD6 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (94886076..95024617, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (94898528..95036531, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene MOB-like protein phocein pseudogene Neighboring gene NADH:ubiquinone oxidoreductase subunit A12 Neighboring gene nuclear receptor subfamily 2 group C member 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial-like Neighboring gene peroxiredoxin-6 pseudogene Neighboring gene 60S ribosomal protein L14 pseudogene Neighboring gene vezatin, adherens junctions transmembrane protein Neighboring gene U6 spliceosomal RNA Neighboring gene microRNA mir-331

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FYVE, RhoGEF and PH domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      94886076..95024617 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152456.2 → XP_015007942.1  FYVE, RhoGEF and PH domain-containing protein 6

      UniProtKB/TrEMBL
      A0A5F8AD44, G7N7Z6
      Related
      ENSMMUP00000075849.1, ENSMMUT00000106779.1
      Conserved Domains (6) summary
      cd13237
      Location:1337 → 1425
      PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
      cd15793
      Location:1078 → 1200
      PH1_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia protein 6, N-terminal Pleckstrin Homology (PH) domain
      cd15743
      Location:1218 → 1278
      FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
      pfam00169
      Location:1337 → 1427
      PH; PH domain
      pfam00621
      Location:876 → 1060
      RhoGEF; RhoGEF domain
      pfam14925
      Location:214 → 464
      HPHLAWLY; Domain of unknown function

    RNA

    1. XR_001448150.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials