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    PHGDH phosphoglycerate dehydrogenase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713480, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PHGDHprovided by VGNC
    Official Full Name
    phosphoglycerate dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:75976
    See related
    Ensembl:ENSMMUG00000023089
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PHGDH in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (104549756..104580156, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (120898244..120928653)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene regenerating family member 4 Neighboring gene 3-hydroxy-3-methylglutaryl-CoA synthase 2 Neighboring gene uncharacterized LOC107000199 Neighboring gene zinc finger protein 697

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphoglycerate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-serine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-3-phosphoglycerate dehydrogenase
    XP_015004857.1
    XP_015004862.1
    XP_015004870.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      104549756..104580156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015149371.2 → XP_015004857.1  D-3-phosphoglycerate dehydrogenase isoform X1

      UniProtKB/TrEMBL
      F7DRL6
      Related
      ENSMMUP00000030404.4, ENSMMUT00000032493.4
      Conserved Domains (2) summary
      COG0111
      Location:7 → 318
      SerA; Phosphoglycerate dehydrogenase or related dehydrogenase [Coenzyme transport and metabolism, General function prediction only]
      cd12173
      Location:8 → 310
      PGDH_4; Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains

    2. XM_015149384.2 → XP_015004870.1  D-3-phosphoglycerate dehydrogenase isoform X3

      UniProtKB/TrEMBL
      F7DRL6
      Conserved Domains (1) summary
      cd12173
      Location:1 → 215
      PGDH_4; Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains

    3. XM_015149376.2 → XP_015004862.1  D-3-phosphoglycerate dehydrogenase isoform X2

      UniProtKB/TrEMBL
      F7DRL6
      Conserved Domains (1) summary
      cd12173
      Location:23 → 235
      PGDH_4; Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains
    Nucleotide Protein
    Heading Accession and Version

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