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    LOC720935 immunoglobulin heavy variable 4-61 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720935, updated on 9-Nov-2023

    Summary

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    Gene symbol
    LOC720935
    Gene description
    immunoglobulin heavy variable 4-61
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    IGH; IGHV; IGHV4; IGHV4-E
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    Genomic context

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    See LOC720935 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (169193472..169194160, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (169166221..169167000)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy variable 3-73-like Neighboring gene immunoglobulin heavy variable 1-3-like Neighboring gene immunoglobulin heavy variable 3-66-like Neighboring gene immunoglobulin heavy variable 1-3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization. Francica JR, et al. Nat Commun, 2015 Apr 10. PMID 25858157, Free PMC Article
    2. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization. Sundling C, et al. J Immunol, 2014 Apr 15. PMID 24623130, Free PMC Article
    3. Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach. Martinez-Murillo P, et al. Immunity, 2017 May 16. PMID 28514687, Free PMC Article
    4. Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles. Vázquez Bernat N, et al. Immunity, 2021 Feb 9. PMID 33484642
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables antigen binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables immunoglobulin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in B cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in complement activation, classical pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis, engulfment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis, recognition IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of B cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in blood microparticle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of immunoglobulin complex, circulating IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    immunoglobulin heavy variable 4-61
    Names
    immunoglobulin heavy chain variable region

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      169193472..169194160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144645.2 → XP_015000131.2  immunoglobulin heavy variable 4-61

      UniProtKB/TrEMBL
      A0A5F7ZLV2
      Conserved Domains (1) summary
      cl11960
      Location:23 → 120
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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