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    MBD4 methyl-CpG binding domain 4, DNA glycosylase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720557, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MBD4provided by VGNC
    Official Full Name
    methyl-CpG binding domain 4, DNA glycosylaseprovided by VGNC
    Primary source
    VGNC:VGNC:74671
    See related
    Ensembl:ENSMMUG00000012723
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MBD4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (147055810..147068052)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (50676354..50688591, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene H1.8 linker histone Neighboring gene rhodopsin Neighboring gene intraflagellar transport 122 Neighboring gene EF-hand calcium binding domain 12 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene 60S ribosomal protein L32-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyrimidine-specific mismatch base pair DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methyl-CpG-binding domain protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      147055810..147068052
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130159.2 → XP_014985645.2  methyl-CpG-binding domain protein 4 isoform X1

      UniProtKB/TrEMBL
      H9G1F3, H9H3K6
      Related
      ENSMMUP00000016705.4, ENSMMUT00000017839.4
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    2. XM_015130161.2 → XP_014985647.2  methyl-CpG-binding domain protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AJH2, H9G1F3
      Related
      ENSMMUP00000077991.1, ENSMMUT00000080939.1
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    3. XM_015130160.2 → XP_014985646.2  methyl-CpG-binding domain protein 4 isoform X2

      UniProtKB/TrEMBL
      H9G1F3
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:444 → 509
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    4. XM_015130163.2 → XP_014985649.2  methyl-CpG-binding domain protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QZ07, H9G1F3
      Related
      ENSMMUP00000053289.2, ENSMMUT00000077997.2
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:445 → 510
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases

    5. XM_028844501.1 → XP_028700334.1  methyl-CpG-binding domain protein 4 isoform X5

      UniProtKB/TrEMBL
      H9G1F3
      Conserved Domains (2) summary
      smart00391
      Location:79 → 155
      MBD; Methyl-CpG binding domain
      cl23768
      Location:444 → 509
      ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
    Nucleotide Protein
    Heading Accession and Version

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