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    HECTD3 HECT domain E3 ubiquitin protein ligase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705051, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HECTD3provided by VGNC
    Official Full Name
    HECT domain E3 ubiquitin protein ligase 3provided by VGNC
    Primary source
    VGNC:VGNC:73240
    Locus tag
    EGK_00692
    See related
    Ensembl:ENSMMUG00000012993
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HECTD3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (179406787..179415515)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (44577954..44586683, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene zinc finger SWIM-type containing 5 Neighboring gene 28S ribosomal protein S17, mitochondrial Neighboring gene uroporphyrinogen decarboxylase Neighboring gene eukaryotic translation initiation factor 2B subunit gamma Neighboring gene E3 ubiquitin-protein ligase CCNB1IP1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase HECTD3
    Names
    HECT domain containing 3
    NP_001244583.1
    XP_014993480.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257654.1 → NP_001244583.1  E3 ubiquitin-protein ligase HECTD3

      See identical proteins and their annotated locations for NP_001244583.1

      Status: PROVISIONAL

      Source sequence(s)
      JU336398
      UniProtKB/TrEMBL
      A0A1D5Q2I9, A0A8J8Y643, F7HR90, G7MGP1
      Related
      ENSMMUP00000017066.2, ENSMMUT00000018229.4
      Conserved Domains (2) summary
      cd08666
      Location:238 → 371
      APC10-HECTD3; APC10-like DOC1 domain of HECTD3, a HECT E3 ubiquitin ligase protein that mediates substrate ubiquitination
      pfam00632
      Location:579 → 845
      HECT; HECT-domain (ubiquitin-transferase)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      179406787..179415515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137994.2 → XP_014993480.1  E3 ubiquitin-protein ligase HECTD3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QYJ5
      Related
      ENSMMUP00000053126.2, ENSMMUT00000066100.2
      Conserved Domains (2) summary
      pfam00632
      Location:302 → 561
      HECT; HECT-domain (ubiquitin-transferase)
      cl02148
      Location:1 → 87
      APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    Nucleotide Protein
    Heading Accession and Version

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