CYP3A4 cytochrome P450 3A64 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: CYP3A4
Gene description: cytochrome P450 3A64
See related: Ensembl:ENSMMUG00000022730
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: CYP3A64
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	3	NC_041756.1 (41932677..41962305, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	3	NC_027895.1 (125264300..125293907, complement)

Chromosome 3 - NC_041756.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

study of genetic variants of CYP3A4 in cynomolgus and rhesus macaques from China
Title: Genetic variants of CYP3A4 and CYP3A5 in cynomolgus and rhesus macaques.

Submit: New GeneRIF Correction

General gene information

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Markers

CYPNOA (e-PCR)
- UniSTS:36431

D7S2874 (e-PCR)
- UniSTS:27061

SHGC-16521 (e-PCR)
- UniSTS:1733

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables estrogen 16-alpha-hydroxylase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables heme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA Inferred from Electronic Annotation more info	PubMed
enables testosterone 6-beta-hydroxylase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in oxidative demethylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in steroid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytochrome P450 3A64

Names: cytochrome P450, family 3, subfamily A, polypeptide 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.