U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MME membrane metalloendopeptidase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707667, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MMEprovided by VGNC
    Official Full Name
    membrane metalloendopeptidaseprovided by VGNC
    Primary source
    VGNC:VGNC:74886
    Locus tag
    EGK_11980
    See related
    Ensembl:ENSMMUG00000006662
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    neprilysin
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MME in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (57349848..57441014)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (142072337..142163500)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676133 Neighboring gene uncharacterized LOC106997032 Neighboring gene polyadenylate-binding protein 1 pseudogene Neighboring gene small transmembrane regulator of ion transport 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amyloid-beta clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    neprilysin
    NP_001247743.1
    XP_014987231.1
    XP_014987232.1
    XP_014987233.1
    XP_014987234.1
    XP_014987235.1
    XP_014987238.1
    XP_014987239.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260814.1 → NP_001247743.1  neprilysin

      See identical proteins and their annotated locations for NP_001247743.1

      Status: PROVISIONAL

      Source sequence(s)
      JV047106
      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Related
      ENSMMUP00000048495.2, ENSMMUT00000063572.2
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      57349848..57441014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015131749.2 → XP_014987235.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Related
      ENSMMUP00000057372.2, ENSMMUT00000071951.2
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    2. XM_015131752.2 → XP_014987238.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    3. XM_015131753.2 → XP_014987239.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    4. XM_015131748.2 → XP_014987234.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    5. XM_015131747.2 → XP_014987233.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    6. XM_015131746.2 → XP_014987232.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

    7. XM_015131745.2 → XP_014987231.1  neprilysin isoform X1

      UniProtKB/TrEMBL
      A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
      Related
      ENSMMUP00000008763.4, ENSMMUT00000009326.4
      Conserved Domains (1) summary
      cd08662
      Location:79 → 748
      M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.