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    PACSIN2 protein kinase C and casein kinase substrate in neurons 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711242, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PACSIN2provided by VGNC
    Official Full Name
    protein kinase C and casein kinase substrate in neurons 2provided by VGNC
    Primary source
    VGNC:VGNC:75745
    Locus tag
    EGK_03119
    See related
    Ensembl:ENSMMUG00000002229
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PACSIN2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (8472544..8617388)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (85021255..85169116, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene TTL family tubulin polyglutamylase complex subunit L1 Neighboring gene uncharacterized LOC114670345 Neighboring gene uncharacterized LOC114670346 Neighboring gene cytochrome c oxidase assembly factor 1 homolog pseudogene Neighboring gene ADP ribosylation factor GTPase activating protein 3 Neighboring gene uncharacterized LOC107000679

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in caveola assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in plasma membrane tubulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein kinase C and casein kinase substrate in neurons protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      8472544..8617388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150504.2 → XP_015005990.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F8A5A7
      Related
      ENSMMUP00000061727.1, ENSMMUT00000109776.1
      Conserved Domains (3) summary
      cd11998
      Location:390 → 445
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:309 → 389
      NPF; Rabosyn-5 repeating NPF sequence-motif
      cl12013
      Location:1 → 234
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_015150501.2 → XP_015005987.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A5A7, H9FPE7
      Conserved Domains (3) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:431 → 486
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:350 → 430
      NPF; Rabosyn-5 repeating NPF sequence-motif

    3. XM_015150503.2 → XP_015005989.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A5A7, A0A5S6RAU3, A0A8J8YPA4, F7GRI7, G7N443
      Related
      ENSMMUP00000007173.3, ENSMMUT00000007636.4
      Conserved Domains (3) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:429 → 484
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:348 → 428
      NPF; Rabosyn-5 repeating NPF sequence-motif

    4. XM_015150506.2 → XP_015005992.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A5F8A5A7, F6XXK2, H9FPE9
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:388 → 443
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    5. XM_015150505.2 → XP_015005991.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A5A7
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:390 → 445
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    6. XM_028827643.1 → XP_028683476.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A5F8A5A7, A0A5K1VQ20
      Related
      ENSMMUP00000036944.3, ENSMMUT00000043947.3
      Conserved Domains (2) summary
      cd11998
      Location:347 → 402
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      cl12013
      Location:1 → 234
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    7. XM_028827638.1 → XP_028683471.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A5A7, H9FPE7
      Conserved Domains (3) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:431 → 486
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:350 → 430
      NPF; Rabosyn-5 repeating NPF sequence-motif

    8. XM_028827642.1 → XP_028683475.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A5F8A5A7
      Conserved Domains (2) summary
      cd11998
      Location:349 → 404
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      cl12013
      Location:1 → 234
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    9. XM_028827640.1 → XP_028683473.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A5A7
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:390 → 445
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    10. XM_015150502.2 → XP_015005988.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A5A7, H9FPE7
      Conserved Domains (3) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:431 → 486
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:350 → 430
      NPF; Rabosyn-5 repeating NPF sequence-motif

    11. XM_015150507.2 → XP_015005993.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A5F8A5A7, F6XXK2, H9FPE9
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:388 → 443
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    12. XM_028827641.1 → XP_028683474.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A5A7
      Conserved Domains (2) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:390 → 445
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2

    13. XM_028827637.1 → XP_028683470.1  protein kinase C and casein kinase substrate in neurons protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A5A7, H9FPE7
      Related
      ENSMMUP00000070549.1, ENSMMUT00000084291.1
      Conserved Domains (3) summary
      cd07679
      Location:18 → 275
      F-BAR_PACSIN2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2)
      cd11998
      Location:431 → 486
      SH3_PACSIN1-2; Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2
      pfam16601
      Location:350 → 430
      NPF; Rabosyn-5 repeating NPF sequence-motif
    Nucleotide Protein
    Heading Accession and Version

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