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    CG10073 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37225, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10073provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034440
    Locus tag
    Dmel_CG10073
    See related
    AllianceGenome:FB:FBgn0034440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10073; FBgn0034440
    Summary
    Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. Is expressed in adult head. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10073 in Genome Data Viewer
    Location:
    56D2-56D2; 2-89 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19380543..19384965)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15268048..15272470)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Succinate dehydrogenase, subunit A (flavoprotein)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Behavioral screening of sleep-promoting effects of human intestinal and food-associated bacteria on Drosophila melanogaster. Ko T, et al. Genes Cells, 2023 Jun. PMID 36914986, Free PMC Article
    2. A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries. Slaidina M, et al. Genome Res, 2021 Oct. PMID 34389661, Free PMC Article
    3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    4. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
    5. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metalloexopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10073-PA
    CG10073-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19380543..19384965
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274161.1 → NP_001261090.1  uncharacterized protein Dmel_CG10073, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261090.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KFC9, Q8SZG3
      Conserved Domains (2) summary
      cd03875
      Location:80 → 387
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
      cl21513
      Location:398 → 638
      NrfD; Polysulphide reductase, NrfD

    2. NM_137573.4 → NP_611417.3  uncharacterized protein Dmel_CG10073, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611417.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBK4, Q8SZG3
      Related
      FBpp0085711
      Conserved Domains (2) summary
      cd03875
      Location:72 → 379
      M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
      cl21513
      Location:390 → 630
      NrfD; Polysulphide reductase, NrfD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KFC9 A0A0B4KFC9
    A1ZBK4 A1ZBK4
    Q8SZG3 Q8SZG3

    Gene LinkOut

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