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    CG18473 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41116, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18473provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037683
    Locus tag
    Dmel_CG18473
    See related
    AllianceGenome:FB:FBgn0037683
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8125; Dmel\CG18473
    Summary
    Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Predicted to be involved in catabolic process. Is expressed in adult head; embryonic Malpighian tubule; embryonic proventriculus; and embryonic/larval corpus allatum. Orthologous to human PTER (phosphotriesterase related). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18473 in Genome Data Viewer
    Location:
    85D11-85D12; 3-48 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9363305..9364838)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5189027..5190560)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene doctor no Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Serine racemase Neighboring gene FER tyrosine kinase Neighboring gene antisense RNA:CR46145

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Fes/Fer non-receptor tyrosine kinase cooperates with Src42A to regulate dorsal closure in Drosophila. Murray MJ, et al. Development, 2006 Aug. PMID 16831834
    2. Microarray analysis of immune challenged Drosophila hemocytes. Johansson KC, et al. Exp Cell Res, 2005 Apr 15. PMID 15777795
    3. A Search for Genes Mediating the Growth-Promoting Function of TGFβ in the Drosophila melanogaster Wing Disc. Hevia CF, et al. Genetics, 2017 May. PMID 28315837, Free PMC Article
    4. A Glio-Protective Role of mir-263a by Tuning Sensitivity to Glutamate. Aw SS, et al. Cell Rep, 2017 May 30. PMID 28564598
    5. Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9. Schwartz S, et al. Genetics, 2016 Jul. PMID 27182943, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18473-PA
    NP_731339.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9363305..9364838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169272.2 → NP_731339.1  uncharacterized protein Dmel_CG18473 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731339.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VHF2
      Related
      FBpp0081503
      Conserved Domains (1) summary
      cd00530
      Location:17 → 346
      PTE; Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHF2.1 Q9VHF2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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