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    CG2875 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2875provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029672
    Locus tag
    Dmel_CG2875
    See related
    AllianceGenome:FB:FBgn0029672
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2875
    Summary
    Predicted to be involved in ribosome biogenesis. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; larval visceral muscle cell; and visceral muscle primordium. Orthologous to human NOC4L (nucleolar complex associated 4 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2875 in Genome Data Viewer
    Location:
    3D6-3D6; 1-3 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3571456..3573622, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3465489..3467655, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44999 Neighboring gene Dpr-interacting protein alpha Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR34335 Neighboring gene pickpocket 8 Neighboring gene Allatostatin A receptor 1 Neighboring gene Insulin-like peptide 7 Neighboring gene Poly(ADP-ribose) glycohydrolase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A transcriptional network controlling glial development in the Drosophila visual system. Bauke AC, et al. Development, 2015 Jun 15. PMID 26015542
    2. Drosophila nucleostemin 3 is required to maintain larval neuroblast proliferation. Johnson PW, et al. Dev Biol, 2018 Aug 1. PMID 29679561, Free PMC Article
    3. WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. David-Morrison G, et al. Dev Cell, 2016 Jan 25. PMID 26812014, Free PMC Article
    4. Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome. Grimberg KB, et al. Mol Cell Biol, 2011 Feb. PMID 21149573, Free PMC Article
    5. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Noc4p-Nop14p complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2875-PA
    CG2875-PB
    CG2875-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3571456..3573622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272290.1 → NP_001259219.1  uncharacterized protein Dmel_CG2875, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259219.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4R2
      Conserved Domains (1) summary
      pfam03914
      Location:286 → 434
      CBF; CBF/Mak21 family

    2. NM_166981.2 → NP_726876.1  uncharacterized protein Dmel_CG2875, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726876.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4R2
      Related
      FBpp0070562
      Conserved Domains (1) summary
      pfam03914
      Location:286 → 434
      CBF; CBF/Mak21 family

    3. NM_130713.3 → NP_570069.1  uncharacterized protein Dmel_CG2875, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570069.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W4R1
      Related
      FBpp0070561
      Conserved Domains (1) summary
      pfam03914
      Location:287 → 435
      CBF; CBF/Mak21 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W4R1 Q9W4R1
    Q9W4R2 Q9W4R2

    Gene LinkOut

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