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    zye zye [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40255, updated on 17-Dec-2024

    Summary

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    Official Symbol
    zyeprovided by FlyBase
    Official Full Name
    zyeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036985
    Locus tag
    Dmel_CG5847
    See related
    AllianceGenome:FB:FBgn0036985
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5847; Dmel\CG5847; Zye; zyp
    Summary
    Predicted to be a structural constituent of chitin-based cuticle. Involved in several processes, including apical constriction; cell-matrix adhesion; and regulation of embryonic cell shape. Located in apical plasma membrane. Is expressed in trichome. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zye in Genome Data Viewer
    Location:
    77C2-77C2; 3-47 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20413604..20424309)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20406704..20417409)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene tribbles Neighboring gene long non-coding RNA:CR45973 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular analysis of the Drosophila miniature-dusky ( m-dy) gene complex: m-dy mRNAs encode transmembrane proteins with similarity to C. elegans cuticulin. DiBartolomeis SM, et al. Mol Genet Genomics, 2002 Jul. PMID 12172795
    2. Mutations in Drosophila crinkled/Myosin VIIA disrupt denticle morphogenesis. Sallee JL, et al. Dev Biol, 2021 Feb. PMID 33248112, Free PMC Article
    3. Trynity models a tube valve in the Drosophila larval airway system. Wang Y, et al. Dev Biol, 2018 May 15. PMID 29518377
    4. A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis. Jaźwińska A, et al. Gene Expr Patterns, 2004 Jul. PMID 15183308
    5. Zona pellucida domain proteins remodel the apical compartment for localized cell shape changes. Fernandes I, et al. Dev Cell, 2010 Jan 19. PMID 20152178

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in apical constriction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in apical constriction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-matrix adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-matrix adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of embryonic cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of embryonic cell shape IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zye
    Names
    CG5847-PA
    zye-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20413604..20424309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140963.2 → NP_649220.1  zye [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649220.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPG1
      Related
      FBpp0077849
      Conserved Domains (1) summary
      smart00241
      Location:61 → 313
      ZP; Zona pellucida (ZP) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPG1 Q9VPG1

    Gene LinkOut

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