Gr66a Gustatory receptor 66a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gr66aprovided by FlyBase
Official Full Name: Gustatory receptor 66aprovided by FlyBase
Primary source: FLYBASE:FBgn0035870
Locus tag: Dmel_CG7189
See related: AllianceGenome:FB:FBgn0035870
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7189; Dmel\CG7189; Gr66; Gr66A; GR66a; GR66A; Gr66C1; GR66C1
Summary: Enables ionotropic taste receptor activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of bitter taste; response to L-canavanine; and response to caffeine. Located in axon and dendrite. Is expressed in several structures, including adult labellum sensillum; gnathal ganglion; gustatory receptor neurons; multidendritic neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (8305336..8306980, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (8298436..8300080, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables ionotropic taste receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables ligand-gated monoatomic ion channel activity	ISS Inferred from Sequence or Structural Similarity more info
enables taste receptor activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in chemosensory behavior	IBA Inferred from Biological aspect of Ancestor more info
involved_in chemosensory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of taste	NAS Non-traceable Author Statement more info	PubMed
involved_in male courtship behavior	IBA Inferred from Biological aspect of Ancestor more info
involved_in monoatomic ion transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to L-canavanine	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to caffeine	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to insecticide	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to toxic substance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sensory perception of bitter taste	IGI Inferred from Genetic Interaction more info	PubMed
involved_in sensory perception of bitter taste	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sensory perception of taste	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of taste	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
is_active_in axon	IBA Inferred from Biological aspect of Ancestor more info
located_in axon	IDA Inferred from Direct Assay more info	PubMed
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in neuronal cell body	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain