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    fon fondue [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35211, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fonprovided by FlyBase
    Official Full Name
    fondueprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032773
    Locus tag
    Dmel_CG15825
    See related
    AllianceGenome:FB:FBgn0032773
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15825; Dmel\CG15825; Fon; FON; Fondue
    Summary
    Involved in hemolymph coagulation and metamorphosis. Located in extracellular region. Is expressed in adult head; adult heart; embryonic/larval fat body; and embryonic/larval hemolymph. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fon in Genome Data Viewer
    Location:
    37D3-37D3; 2-54 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19383138..19386205, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19383138..19386205, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coagulation and survival in Drosophila melanogaster fondue mutants. Bajzek C, et al. J Insect Physiol, 2012 Oct. PMID 22885376
    2. Fondue and transglutaminase in the Drosophila larval clot. Lindgren M, et al. J Insect Physiol, 2008 Mar. PMID 18222466
    3. The Toll immune-regulated Drosophila protein Fondue is involved in hemolymph clotting and puparium formation. Scherfer C, et al. Dev Biol, 2006 Jul 1. PMID 16690050
    4. Clotting factors and eicosanoids protect against nematode infections. Hyrsl P, et al. J Innate Immun, 2011. PMID 20948189
    5. The Drosophila clotting system and its messages for mammals. Theopold U, et al. Dev Comp Immunol, 2014 Jan. PMID 23545286

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in hemolymph coagulation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in hemolymph coagulation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in metamorphosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region HDA PubMed 

    General protein information

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    Preferred Names
    fondue
    Names
    CG15825-PA
    CG15825-PB
    CG15825-PC
    CG15825-PD
    fon-PA
    fon-PB
    fon-PC
    fon-PD
    gpdhdue

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19383138..19386205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136115.4 → NP_609959.1  fondue, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX7
      Related
      FBpp0080763

    2. NM_165287.3 → NP_724177.1  fondue, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724177.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8INW9
      Related
      FBpp0080764

    3. NM_001273641.1 → NP_001260570.1  fondue, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260570.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PDP3

    4. NM_001169542.2 → NP_001163013.1  fondue, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163013.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PDP3 M9PDP3
    Q8INW9 Q8INW9
    Q9VIX7 Q9VIX7

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