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    CG4629 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33284, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4629provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031299
    Locus tag
    Dmel_CG4629
    See related
    AllianceGenome:FB:FBgn0031299
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0257455.15; Dmel\CG4629
    Summary
    Predicted to enable protein serine/threonine kinase activity. Is expressed in adult head; embryonic proventriculus; embryonic proventriculus intermediate layer; embryonic/larval oenocyte; and larval foregut atrium. Orthologous to human NIM1K (NIM1 serine/threonine protein kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4629 in Genome Data Viewer
    Location:
    21E4-21F1; 2-2 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1083091..1102504, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1083091..1102504, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Star Neighboring gene asteroid Neighboring gene Autophagy-related 4a Neighboring gene RNA polymerase mitochondrial Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner. Ellis LL, et al. Genetics, 2011 Jan. PMID 20980240, Free PMC Article
    2. Analysis of the Otd-dependent transcriptome supports the evolutionary conservation of CRX/OTX/OTD functions in flies and vertebrates. Ranade SS, et al. Dev Biol, 2008 Mar 15. PMID 18241855, Free PMC Article
    3. A genomic response to the yeast transcription factor GAL4 in Drosophila. Liu Y, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820459, Free PMC Article
    4. A functional genomic analysis of cell morphology using RNA interference. Kiger AA, et al. J Biol, 2003. PMID 14527345, Free PMC Article
    5. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4629-PE
    CG4629-PF
    NP_608564.3
    • non-AUG (CUG) translation initiation
    NP_722676.3
    • non-AUG (CUG) translation initiation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1083091..1102504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164404.3 → NP_722676.3  uncharacterized protein Dmel_CG4629, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722676.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MS09, Q9VPW3
      Conserved Domains (2) summary
      smart00220
      Location:66 → 321
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14075
      Location:63 → 321
      STKc_NIM1; Catalytic domain of the Serine/Threonine Kinase, NIM1

    2. NM_134720.3 → NP_608564.3  uncharacterized protein Dmel_CG4629, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608564.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MS09, Q9VPW3
      Conserved Domains (2) summary
      smart00220
      Location:66 → 321
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14075
      Location:63 → 321
      STKc_NIM1; Catalytic domain of the Serine/Threonine Kinase, NIM1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MS09 Q8MS09
    Q9VPW3 Q9VPW3

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