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    CG31904 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 319016, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG31904provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260479
    Locus tag
    Dmel_CG31904
    See related
    AllianceGenome:FB:FBgn0260479
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0149848.5; CG31904-PD; Dmel\CG31904
    Old locus tag
    CG31904
    Summary
    Predicted to enable glycine:sodium symporter activity and neurotransmitter transmembrane transporter activity. Predicted to be involved in glycine import across plasma membrane; neurotransmitter transport; and sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult abdomen; adult head; and adult thorax. Human ortholog(s) of this gene implicated in cerebral creatine deficiency syndrome 1 and intellectual disability. Orthologous to several human genes including SLC6A11 (solute carrier family 6 member 11); SLC6A12 (solute carrier family 6 member 12); and SLC6A13 (solute carrier family 6 member 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See CG31904 in Genome Data Viewer
    Location:
    28C2-28C2; 2-28 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7734415..7738809, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7734415..7738809, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46074 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Adult cuticle protein 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glycine:sodium symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables neurotransmitter transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neurotransmitter transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG31904-PB
    CG31904-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7734415..7738809 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164769.2NP_723311.1  uncharacterized protein Dmel_CG31904, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TF4
      Related
      FBpp0079125
      Conserved Domains (2) summary
      pfam15955
      Location:276344
      Cuticle_4; Cuticle protein
      cl00456
      Location:123243
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. NM_164768.2NP_723310.1  uncharacterized protein Dmel_CG31904, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723310.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TF4
      Related
      FBpp0079124
      Conserved Domains (2) summary
      pfam15955
      Location:276344
      Cuticle_4; Cuticle protein
      cl00456
      Location:123243
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain