U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GXMT1 glucuronoxylan 4-O-methyltransferase-like protein (DUF579) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840272, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GXMT1
    Official Full Name
    glucuronoxylan 4-O-methyltransferase-like protein (DUF579)
    Primary source
    TAIR:AT1G33800
    Locus tag
    AT1G33800
    See related
    Araport:AT1G33800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGXMT1; F14M2.8; F14M2_8; glucuronoxylan methyltransferase 1; GXM1
    Summary
    Encodes a glucuronoxylan(GX)-specific 4-O-methyltransferase responsible for methylating GlcA residues in GX. Reduced methylation of GX ingxmt1-1 plants is correlated with altered lignin composition.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GXMT1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (12261165..12262750)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene jacalin lectin family protein Neighboring gene zinc finger/BTB domain protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. 4-O-methylation of glucuronic acid in Arabidopsis glucuronoxylan is catalyzed by a domain of unknown function family 579 protein. Urbanowicz BR, et al. Proc Natl Acad Sci U S A, 2012 Aug 28. PMID 22893684, Free PMC Article
    2. Modification of the degree of 4-O-methylation of secondary wall glucuronoxylan. Yuan Y, et al. Plant Sci, 2014 Apr. PMID 24576763
    3. Three Arabidopsis DUF579 domain-containing GXM proteins are methyltransferases catalyzing 4-o-methylation of glucuronic acid on xylan. Lee C, et al. Plant Cell Physiol, 2012 Nov. PMID 23045523
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The activities of GXM1, GXM2 and GXM3 (this protein) are responsible for all of the glucuronic acid (GlcA) methylation in xylan in stems, and the degree of GlcA methylation in xylan can be modified by altered expression of GXMs.
      Title: Modification of the degree of 4-O-methylation of secondary wall glucuronoxylan.
    2. DUF579 domain-containing proteins, GXM1, GXM2 and GXM3, are methyltransferases catalyzing 4-O-methylation of glucuronic acid side chains on xylan.
      Title: Three Arabidopsis DUF579 domain-containing GXM proteins are methyltransferases catalyzing 4-o-methylation of glucuronic acid on xylan.
    3. An Arabidopsis gene (At1g33800) encodes a cation-dependent glucuronoxylan methyltransferase (GXMT)that specifically methylates O-4 of the GlcA substituents of glucuronoxylan.
      Title: 4-O-methylation of glucuronic acid in Arabidopsis glucuronoxylan is catalyzed by a domain of unknown function family 579 protein.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_103099.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glucuronoxylan 4-O-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lignin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within polysaccharide metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in xylan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within xylan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    glucuronoxylan 4-O-methyltransferase-like protein (DUF579)
    NP_564428.1
    • Protein of unknown function (DUF579); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF579 (InterPro:IPR021148), Conserved hypothetical protein CHP01627 (InterPro:IPR006514); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF579) (TAIR:AT4G09990.1); Has 252 Blast hits to 251 proteins in 20 species: Archae - 0; Bacteria - 5; Metazoa - 0; Fungi - 0; Plants - 240; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      12261165..12262750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103099.2 → NP_564428.1  glucuronoxylan 4-O-methyltransferase-like protein (DUF579) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564428.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LQ32
      UniProtKB/TrEMBL
      A0A178W7W0, A0A5S9WNE6
      Conserved Domains (1) summary
      TIGR01627
      Location:67 → 289
      A_thal_3515; uncharacterized plant-specific domain TIGR01627
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LQ32.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools