SIP1;2 Aquaporin-like superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SIP1;2
Official Full Name: Aquaporin-like superfamily protein
Primary source: TAIR:AT5G18290
Locus tag: AT5G18290
See related: Araport:AT5G18290
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F20L16.1; SIP1B; SMALL AND BASIC INTRINSIC PROTEIN 1B
Summary: Belongs to a family of plant aquaporins.Similar to yeast and radish aquaporins. Located on ER
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Genomic context

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See SIP1;2 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 4

Sequence:: Chromosome: 5; NC_003076.8 (6055028..6058368, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SIP1;2 are the smallest aquaporins. When expressed in yeast gave water-channel activity. They are localized in ER of all tissues except dry seeds. [SIP1;2]
Title: Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001203400.1

Supported by ESTs:

NM_121834.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables water channel activity	IDA Inferred from Direct Assay more info	PubMed
enables water channel activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within water transport	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Aquaporin-like superfamily protein

NP_001190329.1

SIP1;2; FUNCTIONS IN: water channel activity; INVOLVED IN: transport; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: LP.04 four leaves visible, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: small and basic intrinsic protein 1A (TAIR:AT3G04090.1).

NP_197330.1

SIP1;2; FUNCTIONS IN: water channel activity; INVOLVED IN: transport; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: LP.04 four leaves visible, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: small and basic intrinsic protein 1A (TAIR:AT3G04090.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

6055028..6058368 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_121834.2 → NP_197330.1 Aquaporin-like superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_197330.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FK43

UniProtKB/TrEMBL

A0A5S9Y5U6, A0A654G239

Conserved Domains (1) summary

cl00200
Location:114 → 229

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
NM_001203400.1 → NP_001190329.1 Aquaporin-like superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190329.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FK43

UniProtKB/TrEMBL

A0A5S9Y5U6, A0A654G239

Conserved Domains (1) summary

cl00200
Location:114 → 229

MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...