U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    KNAT3 homeobox protein knotted-1-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832593, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    KNAT3
    Official Full Name
    homeobox protein knotted-1-like 3
    Primary source
    TAIR:AT5G25220
    Locus tag
    AT5G25220
    See related
    Araport:AT5G25220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F21J6.18; F21J6_18; KNAT3 HOMEOBOX PROTEIN; KNOTTED1-like homeobox gene 3
    Summary
    A member of class II knotted1-like homeobox gene family (together with KNAT4 and KNAT5). Expressed in: hypocotyl-root boundary, anther-filament junction in flowers, ovule-funiculus and peduncle-silique boundaries, petioles and root. Light-regulated expression with differential response to red/far-red light. KNAT3 promoter activity showed cell-type specific pattern along longitudinal root axis, restricted mainly to the differentiation zone of the root, namely in the cortex and pericycle. Not detected in lateral root primordia
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KNAT3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (8735944..8738601)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribosomal protein S5/Elongation factor G/III/V family protein Neighboring gene stress induced protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Localization of expression of KNAT3, a class 2 knotted1-like gene. Serikawa KA, et al. Plant J, 1997 Apr. PMID 9161040
    2. The class II KNOX transcription factors KNAT3 and KNAT7 synergistically regulate monolignol biosynthesis in Arabidopsis. Qin W, et al. J Exp Bot, 2020 Sep 19. PMID 32474603
    3. The Class II KNOX genes KNAT3 and KNAT7 work cooperatively to influence deposition of secondary cell walls that provide mechanical support to Arabidopsis stems. Wang S, et al. Plant J, 2020 Jan. PMID 31587430
    4. A Role for KNAT Class II Genes in Root Development. Truernit E, et al. Plant Signal Behav, 2007 Jan. PMID 19704797, Free PMC Article
    5. The Class II KNOX family members KNAT3 and KNAT7 redundantly participate in Arabidopsis seed coat mucilage biosynthesis. Zhang Y, et al. J Exp Bot, 2022 Jun 2. PMID 35188965

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Class II KNOX family members KNAT3 and KNAT7 redundantly participate in Arabidopsis seed coat mucilage biosynthesis.
      Title: The Class II KNOX family members KNAT3 and KNAT7 redundantly participate in Arabidopsis seed coat mucilage biosynthesis.
    2. The class II KNOX transcription factors KNAT3 and KNAT7 synergistically regulate monolignol biosynthesis in Arabidopsis.
      Title: The class II KNOX transcription factors KNAT3 and KNAT7 synergistically regulate monolignol biosynthesis in Arabidopsis.
    3. The Class II KNOX genes KNAT3 and KNAT7 work cooperatively to influence deposition of secondary cell walls that provide mechanical support to Arabidopsis stems.
      Title: The Class II KNOX genes KNAT3 and KNAT7 work cooperatively to influence deposition of secondary cell walls that provide mechanical support to Arabidopsis stems.
    4. BLH1 and KNAT3 together modulate seed germination and early seedling development by directly regulating ABI3 expression.
      Title: BLH1 and KNAT3 modulate ABA responses during germination and early seedling development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001036861.1
    NM_122431.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to cytokine stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within detection of cytokinin stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    homeobox protein knotted-1-like 3
    NP_001031938.1
    • KNOTTED1-like homeobox gene 3 (KNAT3); FUNCTIONS IN: transcription activator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to light stimulus, detection of cytokinin stimulus, cellular response to cytokine stimulus; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ELK (InterPro:IPR005539), KNOX1 (InterPro:IPR005540), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), KNOX2 (InterPro:IPR005541), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: KNOTTED1-like homeobox gene 4 (TAIR:AT5G11060.1); Has 6026 Blast hits to 5994 proteins in 341 species: Archae - 0; Bacteria - 2; Metazoa - 2058; Fungi - 371; Plants - 3387; Viruses - 4; Other Eukaryotes - 204 (source: NCBI BLink).
    NP_197904.1
    • KNOTTED1-like homeobox gene 3 (KNAT3); FUNCTIONS IN: transcription activator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: response to light stimulus, detection of cytokinin stimulus, cellular response to cytokine stimulus; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 35 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ELK (InterPro:IPR005539), Homeobox (InterPro:IPR001356), KNOX1 (InterPro:IPR005540), Homeodomain-like (InterPro:IPR009057), KNOX2 (InterPro:IPR005541), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: KNOTTED1-like homeobox gene 4 (TAIR:AT5G11060.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8735944..8738601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122431.3 → NP_197904.1  homeobox protein knotted-1-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197904.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48000, Q8L839, Q8LDC1
      UniProtKB/TrEMBL
      A0A178U9D1, A0A5S9Y771, A0A654G3Y5
      Conserved Domains (3) summary
      pfam03790
      Location:160 → 197
      KNOX1; KNOX1 domain
      pfam03791
      Location:217 → 267
      KNOX2; KNOX2 domain
      pfam05920
      Location:362 → 401
      Homeobox_KN; Homeobox KN domain

    2. NM_001036861.1 → NP_001031938.1  homeobox protein knotted-1-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031938.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y771, A0A654G3Y5, F4JWP8
      Conserved Domains (4) summary
      pfam03789
      Location:322 → 343
      ELK; ELK domain
      pfam03790
      Location:160 → 197
      KNOX1; KNOX1 domain
      pfam03791
      Location:217 → 267
      KNOX2; KNOX2 domain
      pfam05920
      Location:362 → 401
      Homeobox_KN; Homeobox KN domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48000.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools