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    mRpS2 mitochondrial ribosomal protein S2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33688, updated on 9-Dec-2024

    Summary

    Official Symbol
    mRpS2provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein S2provided by FlyBase
    Primary source
    FLYBASE:FBgn0031639
    Locus tag
    Dmel_CG2937
    See related
    AllianceGenome:FB:FBgn0031639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2937; Dmel\CG2937; MRP-S2
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is expressed in adult head; embryonic/larval midgut; and organism. Used to study intrinsic cardiomyopathy. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 36. Orthologous to human MRPS2 (mitochondrial ribosomal protein S2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mRpS2 in Genome Data Viewer
    Location:
    25B1-25B1; 2-14 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4849439..4850419, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4849439..4850419, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mextli Neighboring gene uncharacterized protein Neighboring gene Monensin sensitivity 1 Neighboring gene smog

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of mitochondrial small ribosomal subunit TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial ribosomal protein S2
    Names
    CG2937-PA
    mRpS2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4849439..4850419 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078749.4NP_523473.2  mitochondrial ribosomal protein S2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523473.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MSS7, Q9VR37
      Related
      FBpp0077099
      Conserved Domains (1) summary
      cd01425
      Location:63238
      RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...