Slc35e2 solute carrier family 35, member E2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slc35e2provided by MGI
Official Full Name: solute carrier family 35, member E2provided by MGI
Primary source: MGI:MGI:2444240
See related: Ensembl:ENSMUSG00000042202 AllianceGenome:MGI:2444240
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Slc35e2a; A530082C11Rik
Summary: Predicted to enable antiporter activity. Acts upstream of or within blastocyst hatching. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cardiovascular system; central nervous system; endocrine gland; genitourinary system; and trachea. Orthologous to several human genes including SLC35E2B (solute carrier family 35 member E2B). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in genital fat pad adult (RPKM 6.1), adrenal adult (RPKM 5.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 4 E2; 4 86.62 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (155685873..155707797)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (155601416..155623340)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.
Title: SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AI957035 (e-PCR)
- UniSTS:165380

Slc35e2 (e-PCR), detects polymorphism
- UniSTS:547094

AU016090 (e-PCR)
- UniSTS:207742

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables antiporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blastocyst hatching	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: solute carrier family 35 member E2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.