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    wbpW phosphomannose isomerase/mannose-1-phosphate guanylyl transferase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 883088, updated on 24-Aug-2024

    Summary

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    Gene symbol
    wbpW
    Gene description
    phosphomannose isomerase/mannose-1-phosphate guanylyl transferase
    Locus tag
    PA5452
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (6141666..6143105, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene glycosyltransferase WbpY Neighboring gene glycosyltransferase WbpX Neighboring gene ABC transporter Neighboring gene LPS efflux transporter membrane protein Neighboring gene GDP-mannose 4,6-dehydratase Neighboring gene oxidoreductase Rmd Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Synthesis of the A-band polysaccharide sugar D-rhamnose requires Rmd and WbpW: identification of multiple AlgA homologues, WbpW and ORF488, in Pseudomonas aeruginosa. Rocchetta HL, et al. Mol Microbiol, 1998 Sep. PMID 9781879
    2. Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production. Byrd MS, et al. Mol Microbiol, 2009 Aug. PMID 19659934, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within GDP-mannose biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within O antigen biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within lipopolysaccharide biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphomannose isomerase/mannose-1-phosphate guanylyl transferase
    NP_254139.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      6141666..6143105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_254139.1 phosphomannose isomerase/mannose-1-phosphate guanylyl transferase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_254139.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      O87266
      Conserved Domains (1) summary
      cl11394
      Location:2 → 477
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein
    Heading Accession and Version

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