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    MAP3K14-AS1 MAP3K14 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100133991, updated on 10-Dec-2024

    Summary

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    Official Symbol
    MAP3K14-AS1provided by HGNC
    Official Full Name
    MAP3K14 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:44359
    See related
    AllianceGenome:HGNC:44359
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 9.5), lymph node (RPKM 2.6) and 17 other tissues See more
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    Genomic context

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    See MAP3K14-AS1 in Genome Data Viewer
    Location:
    17q21.31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (45247925..45268630)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (46101671..46122414)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (43325292..43345997)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene FMNL1 divergent transcript Neighboring gene ReSE screen-validated silencer GRCh37_chr17:43279930-43280114 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:43281002-43281263 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8612 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8613 Neighboring gene Sharpr-MPRA regulatory region 174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43300291-43300791 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12283 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12284 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12288 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12289 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43305824-43306459 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12291 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8615 Neighboring gene formin like 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43318529-43319247 Neighboring gene FMNL1 antisense RNA 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:43322845-43323015 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12292 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12293 Neighboring gene EF-hand calcium binding domain 15, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43333269-43334029 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8617 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43339293-43339898 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:43339899-43340502 Neighboring gene spermatogenesis associated 32 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:43344006-43345205 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:43350360-43351334 Neighboring gene mitogen-activated protein kinase kinase kinase 14 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:43367837-43368040 Neighboring gene Sharpr-MPRA regulatory region 11783 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12295 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12296 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8619 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12297 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12298 Neighboring gene RNA, 5S ribosomal pseudogene 443 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:43414932-43415093 Neighboring gene OCT4 hESC enhancer GRCh37_chr17:43427135-43427636 Neighboring gene uncharacterized LOC105371796

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • FLJ18471, FLJ18606

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024434.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks two exons and contains an alternate 5' exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AK311429, DB133288

    2. NR_024435.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC003963, AK311429, BC031942, DB466340

    3. NR_110324.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AK311429, AK311564, DB466340

    4. NR_110325.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two exons and contains three alternate 5' exons, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AK311429, AL710937, DB133288

    5. NR_110326.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks two exons and contains two alternate 5' exons, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AK311429, DB133288, DB294632

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      45247925..45268630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      46101671..46122414
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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