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    Zfp800 zinc finger protein 800 [ Mus musculus (house mouse) ]

    Gene ID: 627049, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp800provided by MGI
    Official Full Name
    zinc finger protein 800provided by MGI
    Primary source
    MGI:MGI:1889334
    See related
    Ensembl:ENSMUSG00000039841 AllianceGenome:MGI:1889334
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf800
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Acts upstream of or within acinar cell differentiation and endocrine pancreas development. Predicted to be located in nucleus. Orthologous to human ZNF800 (zinc finger protein 800). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 3.2), liver E14.5 (RPKM 3.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp800 in Genome Data Viewer
    Location:
    6 A3.2- A3.3; 6 11.99 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (28210543..28398010, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (28210548..28398033, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene glutamate receptor, metabotropic 8 Neighboring gene STARR-seq mESC enhancer starr_15404 Neighboring gene microRNA 592 Neighboring gene STARR-seq mESC enhancer starr_15405 Neighboring gene STARR-seq mESC enhancer starr_15406 Neighboring gene predicted gene, 52896 Neighboring gene RIKEN cDNA 6530409C15 gene Neighboring gene STARR-seq mESC enhancer starr_15407 Neighboring gene STARR-seq mESC enhancer starr_15408 Neighboring gene STARR-seq mESC enhancer starr_15409 Neighboring gene STARR-positive B cell enhancer mm9_chr6:28371614-28371915 Neighboring gene kelch domain containing pseudogene Neighboring gene fascin actin-bundling protein 3 Neighboring gene golgi coiled coil 1 Neighboring gene ARF GTPase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development. Osipovich AB, et al. Development, 2021 Mar 21. PMID 33653874, Free PMC Article
    2. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A developmental lineage-based gene co-expression network for mouse pancreatic beta-cells reveals a role for Zfp800 in pancreas development.
      Title: A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within acinar cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within endocrine pancreas development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 800

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081678.3 → NP_001075147.1  zinc finger protein 800 isoform a

      See identical proteins and their annotated locations for NP_001075147.1

      Status: VALIDATED

      Source sequence(s)
      AC068501
      Consensus CDS
      CCDS39445.1
      UniProtKB/Swiss-Prot
      Q0VEE6
      UniProtKB/TrEMBL
      B7ZMR9
      Related
      ENSMUSP00000110976.3, ENSMUST00000115321.9
      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger

    2. NM_001364595.2 → NP_001351524.1  zinc finger protein 800 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC068501
      Consensus CDS
      CCDS39445.1
      UniProtKB/Swiss-Prot
      Q0VEE6
      UniProtKB/TrEMBL
      B7ZMR9
      Related
      ENSMUSP00000110975.2, ENSMUST00000115320.8
      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger

    3. NM_001364596.2 → NP_001351525.1  zinc finger protein 800 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC068501, AC068608
      Consensus CDS
      CCDS39445.1
      UniProtKB/Swiss-Prot
      Q0VEE6
      UniProtKB/TrEMBL
      B7ZMR9
      Related
      ENSMUSP00000039222.5, ENSMUST00000035930.11
      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger

    4. NM_001411802.1 → NP_001398731.1  zinc finger protein 800 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC068501
      UniProtKB/Swiss-Prot
      Q0VEE6
      UniProtKB/TrEMBL
      B7ZMR9

    5. NM_001411803.1 → NP_001398732.1  zinc finger protein 800 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC068501
      UniProtKB/Swiss-Prot
      Q0VEE6
      UniProtKB/TrEMBL
      B7ZMR9

    6. NM_001411804.1 → NP_001398733.1  zinc finger protein 800 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC068501

    7. NM_001411805.1 → NP_001398734.1  zinc finger protein 800 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC068501

    8. NM_001411806.1 → NP_001398735.1  zinc finger protein 800 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC068501

    9. NM_001411807.1 → NP_001398736.1  zinc finger protein 800 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC068501

    10. NM_001411808.1 → NP_001398737.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501

    11. NM_001411809.1 → NP_001398738.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501

    12. NM_001411810.1 → NP_001398739.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501

    13. NM_001411811.1 → NP_001398740.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501

    14. NM_001411812.1 → NP_001398741.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501, AC068608

    15. NM_001411813.1 → NP_001398742.1  zinc finger protein 800 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC068501, AC068608

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      28210543..28398010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241073.4 → XP_011239375.1  zinc finger protein 800 isoform X1

      See identical proteins and their annotated locations for XP_011239375.1

      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger

    2. XM_006505149.4 → XP_006505212.1  zinc finger protein 800 isoform X1

      See identical proteins and their annotated locations for XP_006505212.1

      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger

    3. XM_006505148.5 → XP_006505211.1  zinc finger protein 800 isoform X1

      See identical proteins and their annotated locations for XP_006505211.1

      Conserved Domains (5) summary
      sd00018
      Location:616 → 638
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:486 → 506
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:616 → 638
      zf-C2H2; Zinc finger, C2H2 type
      pfam16622
      Location:357 → 383
      zf-C2H2_11; zinc-finger C2H2-type
      pfam16624
      Location:391 → 483
      zf-C2H2_assoc2; Unstructured region upstream of a zinc-finger
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VEE6.1 GenPept UniProtKB/Swiss-Prot:Q0VEE6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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