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    Cyp4x1 cytochrome P450, family 4, subfamily x, polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 81906, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cyp4x1provided by MGI
    Official Full Name
    cytochrome P450, family 4, subfamily x, polypeptide 1provided by MGI
    Primary source
    MGI:MGI:1932403
    See related
    Ensembl:ENSMUSG00000047155 AllianceGenome:MGI:1932403
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CYP_a; CYPIVX1; A230025G20; Cyp4a28-ps
    Summary
    Predicted to enable anandamide 14,15 epoxidase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; heart; nervous system; and neural retina. Orthologous to human CYP4X1 (cytochrome P450 family 4 subfamily X member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 3.7), cortex adult (RPKM 2.3) and 4 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cyp4x1 in Genome Data Viewer
    Location:
    4 D1; 4 52.76 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (114963518..114991276, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (115106323..115134079, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33786 Neighboring gene T cell acute lymphocytic leukemia 1 Neighboring gene PDZK1 interacting protein 1 Neighboring gene cytochrome P450, family 4, subfamily a, polypeptide 28, pseudogene Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1, opposite strand Neighboring gene STARR-seq mESC enhancer starr_11108 Neighboring gene STARR-seq mESC enhancer starr_11109 Neighboring gene STARR-seq mESC enhancer starr_11111 Neighboring gene STARR-seq mESC enhancer starr_11112 Neighboring gene adaptor-related protein complex 2, beta 1 subunit pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (3)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables anandamide 14,15 epoxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables anandamide 14,15 epoxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 4X1
    NP_001003947.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003947.3NP_001003947.1  cytochrome P450 4X1

      See identical proteins and their annotated locations for NP_001003947.1

      Status: VALIDATED

      Source sequence(s)
      AL645473
      Consensus CDS
      CCDS18488.1
      UniProtKB/Swiss-Prot
      Q2HJC6, Q6A152, Q8BYS0
      UniProtKB/TrEMBL
      A2A9Y7
      Related
      ENSMUSP00000102155.2, ENSMUST00000106545.8
      Conserved Domains (1) summary
      pfam00067
      Location:47499
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      114963518..114991276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)