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    Ccnb1ip1 cyclin B1 interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 239083, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccnb1ip1provided by MGI
    Official Full Name
    cyclin B1 interacting protein 1provided by MGI
    Primary source
    MGI:MGI:2685134
    See related
    Ensembl:ENSMUSG00000071470 AllianceGenome:MGI:2685134
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mei4; Gm288; Hei10
    Summary
    Predicted to enable identical protein binding activity. Involved in chiasma assembly. Acts upstream of or within blastocyst formation and spermatid development. Located in condensed nuclear chromosome. Colocalizes with synaptonemal complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CCNB1IP1 (cyclin B1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 2.9) See more
    Orthologs
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    Genomic context

    See Ccnb1ip1 in Genome Data Viewer
    Location:
    14 C1; 14 26.25 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51026706..51033185, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (50789249..50795728, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily H member 4 Neighboring gene tetratricopeptide repeat domain 5 Neighboring gene STARR-positive B cell enhancer ABC_E753 Neighboring gene ribonuclease P RNA component H1 Neighboring gene poly (ADP-ribose) polymerase family, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables ubiquitin-protein transferase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within chiasma assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chiasma assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein ubiquitination TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in reciprocal meiotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with synaptonemal complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase CCNB1IP1
    Names
    RING-type E3 ubiquitin transferase CCNB1IP1
    NP_001104589.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111119.1NP_001104589.1  E3 ubiquitin-protein ligase CCNB1IP1

      See identical proteins and their annotated locations for NP_001104589.1

      Status: PROVISIONAL

      Source sequence(s)
      AC027184
      Consensus CDS
      CCDS49477.1
      UniProtKB/Swiss-Prot
      D3Z3K2
      Related
      ENSMUSP00000093622.4, ENSMUST00000095932.5
      Conserved Domains (2) summary
      pfam13851
      Location:115163
      GAS; Growth-arrest specific micro-tubule binding
      pfam14634
      Location:1052
      zf-RING_5; zinc-RING finger domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      51026706..51033185 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)