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    Chst9 carbohydrate sulfotransferase 9 [ Mus musculus (house mouse) ]

    Gene ID: 71367, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Chst9provided by MGI
    Official Full Name
    carbohydrate sulfotransferase 9provided by MGI
    Primary source
    MGI:MGI:1918617
    See related
    Ensembl:ENSMUSG00000047161 AllianceGenome:MGI:1918617
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GalNAc4ST-2; galNAc-4-ST2; 5430438D01Rik
    Summary
    Enables N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in proteoglycan biosynthetic process and sulfur compound metabolic process. Predicted to be located in Golgi membrane. Orthologous to human CHST9 (carbohydrate sulfotransferase 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Chst9 in Genome Data Viewer
    Location:
    18 A1; 18 8.85 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (15584830..15893214, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (15451773..15760157, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A830021F12 gene Neighboring gene aquaporin 4 Neighboring gene fibrillarin pseudogene Neighboring gene STARR-seq mESC enhancer starr_43888 Neighboring gene STARR-seq mESC enhancer starr_43889 Neighboring gene predicted gene, 30452 Neighboring gene STARR-seq mESC enhancer starr_43890 Neighboring gene STARR-seq mESC enhancer starr_43891 Neighboring gene STARR-seq mESC enhancer starr_43892 Neighboring gene STARR-seq mESC enhancer starr_43893 Neighboring gene predicted gene, 54036 Neighboring gene STARR-seq mESC enhancer starr_43895 Neighboring gene ribosomal protein L11 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAcbeta1-4GlcNAcbeta1-octyl. Okuda T, et al. J Biochem, 2003 Jul. PMID 12944377
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130338

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dermatan 4-sulfotransferase IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dermatan 4-sulfotransferase ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sulfur compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carbohydrate sulfotransferase 9
    Names
    N-acetylgalactosamine-4-O-sulfotransferase 2
    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
    galNAc-4-O-sulfotransferase 2
    NP_001351921.1
    NP_951010.1
    XP_017173481.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364992.1 → NP_001351921.1  carbohydrate sulfotransferase 9 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC102397, AK017407
      UniProtKB/TrEMBL
      Q3KNB9
      Conserved Domains (1) summary
      pfam03567
      Location:133 → 362
      Sulfotransfer_2; Sulfotransferase family

    2. NM_199055.3 → NP_951010.1  carbohydrate sulfotransferase 9 isoform 1

      See identical proteins and their annotated locations for NP_951010.1

      Status: VALIDATED

      Source sequence(s)
      AC102397, AC102416, AC157900
      Consensus CDS
      CCDS29074.1
      UniProtKB/Swiss-Prot
      Q76EC5
      UniProtKB/TrEMBL
      Q3KNB9
      Related
      ENSMUSP00000049975.7, ENSMUST00000053017.13
      Conserved Domains (1) summary
      pfam03567
      Location:179 → 408
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      15584830..15893214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317992.3 → XP_017173481.1  carbohydrate sulfotransferase 9 isoform X1

      UniProtKB/TrEMBL
      Q3KNB9
      Conserved Domains (1) summary
      pfam03567
      Location:115 → 344
      Sulfotransfer_2; Sulfotransferase family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q76EC5.1 GenPept UniProtKB/Swiss-Prot:Q76EC5

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