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    Zfr2 zinc finger RNA binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 103406, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfr2provided by MGI
    Official Full Name
    zinc finger RNA binding protein 2provided by MGI
    Primary source
    MGI:MGI:2143792
    See related
    Ensembl:ENSMUSG00000034949 AllianceGenome:MGI:2143792
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1086; 2010013I23Rik; 9130206N08Rik
    Summary
    Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Is expressed in cortical plate. Orthologous to human ZFR2 (zinc finger RNA binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in cortex adult (RPKM 14.6), frontal lobe adult (RPKM 13.3) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfr2 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81068967..81087957)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81233133..81252123)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ataxia, cerebellar, Cayman type, opposite strand Neighboring gene nicotinamide riboside kinase 2 Neighboring gene ataxia, cerebellar, Cayman type Neighboring gene megakaryocyte-associated tyrosine kinase Neighboring gene STARR-positive B cell enhancer ABC_E6886 Neighboring gene mitochondrial ribosomal protein L54

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse. Cauchi LM, et al. Dev Biol, 2022 Sep. PMID 35679955
    2. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
    3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse.
      Title: Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger RNA-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034895.3 → NP_001030067.2  zinc finger RNA-binding protein 2

      Status: VALIDATED

      Source sequence(s)
      AC155932, AK033649, AW045600, BB641594, BF449481, BQ042879, CB249573
      Consensus CDS
      CCDS48642.1
      UniProtKB/TrEMBL
      E9Q5M4
      Related
      ENSMUSP00000113913.2, ENSMUST00000117798.8
      Conserved Domains (4) summary
      smart00451
      Location:205 → 232
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:207 → 253
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam09786
      Location:72 → 169
      CytochromB561_N; Cytochrome B561, N terminal
      cl02675
      Location:586 → 837
      DZF; DZF domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      81068967..81087957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001779403.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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