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    Pcdhb18 protocadherin beta 18 [ Mus musculus (house mouse) ]

    Gene ID: 93889, updated on 27-Nov-2024

    Summary

    Official Symbol
    Pcdhb18provided by MGI
    Official Full Name
    protocadherin beta 18provided by MGI
    Primary source
    MGI:MGI:2136756
    See related
    Ensembl:ENSMUSG00000048347 AllianceGenome:MGI:2136756
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pcdhb9; PcdhbR
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be active in plasma membrane. Orthologous to human PCDHB10 (protocadherin beta 10) and PCDHB9 (protocadherin beta 9). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Pcdhb18 in Genome Data Viewer
    Location:
    18 B3; 18 19.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (37622524..37627558)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (37489465..37494503)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene protocadherin alpha 4B Neighboring gene predicted gene, 38666 Neighboring gene predicted gene, 38667 Neighboring gene protocadherin beta 16 Neighboring gene protocadherin beta 17 Neighboring gene protocadherin beta 19 Neighboring gene protocadherin beta 20

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    General gene information

    Clone Names

    • MGC107468

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protocadherin beta-18
    Names
    PCDH-beta-18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053143.3NP_444373.1  protocadherin beta-18 precursor

      See identical proteins and their annotated locations for NP_444373.1

      Status: VALIDATED

      Source sequence(s)
      AC020967
      Consensus CDS
      CCDS29184.1
      UniProtKB/Swiss-Prot
      Q91Y02
      UniProtKB/TrEMBL
      Q3USI6
      Related
      ENSMUSP00000052113.3, ENSMUST00000055949.4
      Conserved Domains (3) summary
      cd11304
      Location:247343
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08266
      Location:32112
      Cadherin_2; Cadherin-like
      pfam16492
      Location:688771
      Cadherin_C_2; Cadherin cytoplasmic C-terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      37622524..37627558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)